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Updated: Jan 20, 2026
A Mouse Model of Ankle-Subtalar Complex Joint Instability
Published on: October 28, 2022
Exercise improves physical function in young women with functional ankle instability: a randomized controlled trial
Qianwen Liao1, Borui Zhang1, Yuan Fang1
1Department of Health and Physical Education, The Education University of Hong Kong, Tai Po, Hong Kong Special Administrative Region of China.
Background:
Prolonged sedentary behavior in women is associated with weakened lower-body musculature and increased risk of falls and injury. Although high-intensity circuit training (HICT) has been reported to effectively improve aerobic and anaerobic fitness in previously inactive individuals, few studies have evaluated its effectiveness in young women with functional ankle instability (FAI).
Objective:
We aimed to evaluate the effect of an 8-week HICT program on balance, ankle stability, and physical fitness in sedentary young women with FAI.
Method:
This randomized controlled trial included 96 sedentary young women with FAI (aged 18-30 years, Cumberland Ankle Instability Tool (CAIT) < 25), who were randomly assigned to the HICT (n = 54) or control (n = 42) groups. The HICT group completed an 8-week program (3 sessions/week) with progressive intensity stages, whereas the control group maintained routine activity. A battery of outcomes was assessed before and after the intervention. The primary outcomes included objectively measured balance function and perceived ankle stability, whereas the secondary outcomes included body composition, body circumference, and physical fitness. Repeated-measures analysis of covariance was used to detect the time × group interaction effect, with adjustment for baseline values.
Results:
A significant time × group interaction effect (p < 0.05) was observed for balance function and ankle stability (F = 4.732-54.806, η 2 = 0.048-0.496), body composition (i.e., reductions in hip and thigh circumference: F = 5.092-8.933, η 2 = 0.061-0.213), and physical fitness (i.e., improvements in back and leg strength, flexibility, upper limb strength, and abdominal strength: F = 7.783-54.806, η 2 = 0.082-0.386).
Conclusions:
An 8-week HICT program appears to effectively improve balance and ankle stability in sedentary young women with FAI, providing preliminary evidence that HICT is a promising intervention for enhancing physical function and reducing the risk of falls and injuries in this population.
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