Ultra-Sensitive Detection of Bone Metastasis From Accessory Breast Cancer Using HER2 PET/CT: A Case Report

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Updated: Jan 20, 2026

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Published on: January 22, 2018

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Lei Yang1, Dongling Zhu, Shuang Song

  • 1Department of Nuclear Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology.

Clinical Nuclear Medicine
|January 19, 2026
PubMed

We presented the imaging findings of 18 F-FDG and 68 Ga-HER2 affibody PET/CT in a 52-year-old woman with HER2-positive accessory breast cancer in the right axilla. 18 F-FDG and HER2 PET/CT showed avid uptake of multiple axillary lesions. HER2 PET/CT identified extensive bone metastases with intense uptake, while the ⁹⁹ᵐTc-MDP whole bone scan was negative, and only a few bone lesions with mild tracer uptake were detected by 18 F-FDG PET/CT. Following 6 cycles of the TCbHP regimen, the axillary lesions markedly reduced. This case demonstrates that HER2 PET/CT enables more sensitive detection of HER2-positive lesions, thereby allowing for precise staging and guiding HER2-targeted therapy.

Keywords:
HER2 PET/CTHER2-targeted therapyaccessory breast cancerbone metastases

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