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Pancreatic Juice and Secretion01:26

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Pancreatic juice is a clear fluid produced by the pancreas, containing water, salts, sodium bicarbonate, and enzymes vital for digestion in the small intestine. It helps break down large molecules, facilitating nutrient absorption.
When acidic chyme from the stomach enters the duodenum, it triggers the release of secretin, a hormone that prompts pancreatic juice secretion. After a fatty meal, cholecystokinin, another hormone, stimulates gallbladder contraction and enhances enzyme-rich...
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Acute Pancreatitis I: Introduction01:27

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Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
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Chronic Pancreatitis I: Introduction01:24

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The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
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Chronic Pancreatitis II: Collaborative Care01:29

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The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
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Acute Pancreatitis II: Clinical Manifestations and Management01:30

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Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
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Glucose Homeostasis: Pancreatic Islets and Insulin Secretion01:27

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The pancreatic islets comprising only 1%-2% of the volume are highly vascularized and innervated mini-organs. They contain five endocrine cell types, including β cells that secrete insulin, which is synthesized as a single polypeptide chain, preproinsulin, processed to proinsulin, and finally to insulin and C-peptide. This process is complex and regulated, involving the Golgi complex, the endoplasmic reticulum, and the secretory granules of the β cell.
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Updated: Jan 21, 2026

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Paediatric necrotising pancreatitis.

Nelithma DeSilva1, Baci Alder2, Amit Saha2,3

  • 1Curtin Medical School, Perth, Western Australia, Bentley, Western Australia, Australia.

BMJ Case Reports
|January 19, 2026
PubMed
Summary
This summary is machine-generated.

Necrotising pancreatitis is a rare but serious condition in children. Early recognition of acute pancreatitis in pediatric patients with non-specific abdominal symptoms is crucial for timely diagnosis and treatment.

Keywords:
Gastrointestinal systemPaediatric SurgeryPaediatricsPancreas and biliary tractPancreatitis

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Area of Science:

  • Pediatric Gastroenterology
  • Pancreatology

Background:

  • Necrotising pancreatitis is a severe complication of acute pancreatitis in children.
  • It can present with non-specific symptoms, delaying diagnosis.

Purpose of the Study:

  • To report a case of idiopathic necrotising pancreatitis in a toddler.
  • To highlight the importance of considering acute pancreatitis in pediatric patients with vague abdominal symptoms.

Main Methods:

  • Case report of a toddler with vomiting, pallor, and irritability.
  • Diagnostic workup included laboratory tests and contrast-enhanced CT scan.
  • Management involved supportive care.

Main Results:

  • Diagnosis of necrotising pancreatitis was confirmed by elevated inflammatory markers, lipase, and CT findings.
  • The patient recovered after 9 days of supportive care.
  • Follow-up imaging showed resolution of peripancreatic fluid without long-term complications.

Conclusions:

  • Idiopathic necrotising pancreatitis can occur unexpectedly in young children.
  • Prompt evaluation for acute pancreatitis is essential in pediatric patients presenting with non-specific abdominal symptoms.
  • Early diagnosis and supportive care can lead to favorable outcomes.