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Nonlinear associations between maternal depressive symptoms and children's mental health: a cross-sectional study
Fenling Feng1,2, Xin Zhang3, Jihua Hu4,5
1Department of pediatrics, Xi'an International Medical Center Hospital, Xi'an, Shaanxi, China.
Insights
Maternal depressive symptoms show a nonlinear link to child mental health. Associations are strongest below certain symptom thresholds, weakening significantly above them.
Area of Science:
- Child Psychology
- Maternal Mental Health
- Epidemiology
Background:
- Maternal depressive symptoms (MDS) are linked to offspring mental health.
- The nonlinear nature of this relationship requires further investigation.
Purpose of the Study:
- To examine nonlinear dose-response relationships between MDS and child mental health in preschoolers.
- Focus on preschool-aged children in western China.
Main Methods:
- Cross-sectional study of 17,115 mother-child dyads.
- MDS assessed via CES-D; child mental health via SDQ maternal reports.
- Data collected from kindergartens in western China.
Main Results:
- 16.14% of mothers reported elevated depressive symptoms (CES-D ≥ 16).
- Nonlinear dose-response relationships observed with specific turning points for difficulties and prosocial behavior.
- Associations were stronger below thresholds, weakening above them.
Conclusions:
- Distinct nonlinear dose-response associations exist between MDS and child mental health in western China.
- The strength of association varies below and above specific symptom thresholds.
- Findings highlight the complexity of the maternal depression-child mental health link.
Background:
While associations between maternal depressive symptoms (MDS) and offspring mental health have been documented, the precise nature of this relationship, particularly potential nonlinear patterns, remains insufficiently characterized.
Objective:
This study sought to examine potential nonlinear dose-response relationships between MDS and child mental health among preschool-aged children.
Methods:
We conducted a cross-sectional investigation enrolling 17,115 mother-child dyads from kindergartens in a city in western China. MDS were assessed using the Center for Epidemiologic Studies Depression Scale (CES-D). Children's mental health was assessed via maternal reports using the Strengths and Difficulties Questionnaire (SDQ). Data were collected between February 28 and March 5, 2025.
Results:
Among the 17,115 mother-child dyads, 16.14% (n = 2,763) of mothers (mean age: 34.49 ± 4.65 years) reported elevated depressive symptoms (CES-D score ≥ 16). A nonlinear dose-response relationship was observed, with turning points at maternal CES-D scores of 17 for total difficulties and internalizing problems, 21 for externalizing problems, and 14 for prosocial behavior problems. Below these thresholds, stronger associations were observed (OR = 1.20 for total difficulties, OR = 1.16 for internalizing problems, OR = 1.10 for externalizing problems, and OR = 1.11 for prosocial behavior problems), while above the thresholds, the associations were substantially weakened.
Conclusion:
This cross-sectional study identified distinctive nonlinear dose-response associations between MDS and children's mental health outcomes in a western Chinese city. The associations were stronger below specific thresholds while weakening above these thresholds. These findings warrant further investigation and validation.
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