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Updated: Jan 21, 2026

Experimental Models for Study of Retinal Pigment Epithelial Physiology and Pathophysiology
Published on: November 6, 2010
Severe Permanent Visual Decline After Hypotony-Induced Retinal Pigment Epithelial Changes.
Konstantinos Benekos1, Konstantina Gorgoli1, Panagiotis Laspas1
1Ophthalmology Department, University Hospital of Ioannina, Ioannina, GRC.
A rare case of irreversible vision loss after glaucoma surgery highlights how short-term hypotony maculopathy and choroidal detachment can cause permanent retinal pigment epithelium damage.
Area of Science:
- Ophthalmology
- Glaucoma Surgery
- Retinal Diseases
Background:
- Postoperative hypotony, choroidal effusions, and maculopathy are known risks of glaucoma shunt surgery.
- Uveitis-glaucoma-hyphema (UGH) syndrome can lead to high intraocular pressure (IOP) and vision loss.
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