Related Experiment Video
Updated: Jan 21, 2026

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
Intestinal Angioedema Induced by Angiotensin-Converting Enzyme Inhibitors: A Diagnosis of Exclusion
Rita Pera1, Sara Sá1, João Lagarteira1
1Internal Medicine Department, Unidade Local de Saúde do Nordeste, Bragança, PRT.
None:
Angiotensin-converting enzyme inhibitor (ACEI)-induced intestinal angioedema is a rare and frequently underdiagnosed condition, often presenting with nonspecific gastrointestinal symptoms that can mimic inflammatory, infectious, or neoplastic diseases. We report the case of a 42-year-old female patient who recently started perindopril (an ACEI) for uncontrolled hypertension and developed recurrent abdominal pain and diarrhea. Extensive laboratory and imaging workup, complemented by endoscopic and histological evaluations, did not identify any alternative etiology. Symptoms resolved completely after discontinuation of perindopril, confirming ACEI-induced intestinal angioedema. Early recognition of this entity is essential to avoid invasive procedures and ensure complete resolution with simple drug discontinuation.
Related Concept Videos
Antihypertensive Drugs: Angiotensin-Converting Enzyme Inhibitors
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Enzymes
Enzyme deficiencies can often translate into life-threatening diseases. For example, a genetic abnormality resulting in the deficiency of the enzyme G6PD...
The Pauli Exclusion Principle
Eukaryotic Transcription Inhibitors
Eukaryotic transcription inhibitors usually contain two distinct domains, a...
Enzyme Kinetics
Scientists typically study enzyme kinetics with a fixed amount of enzyme in the controlled environment of a test tube. When more reactant, or substrate, is...

