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Massive Submacular Hemorrhage Following Intravitreal Faricimab Injection for Neovascular Age-Related Macular
Adriana Kaganovski1, Nairi Rostomian1, Eric Shrier1
1Ophthalmology, State University of New York Downstate Medical Center, Brooklyn, USA.
None:
We report a case of massive submacular hemorrhage (SMH) in a patient with neovascular age-related macular degeneration (AMD) occurring three days after intravitreal faricimab injection. While faricimab has demonstrated a favorable safety profile and lower hemorrhagic events compared to other anti-vascular endothelial growth factor agents, SMH, in specific, is not listed among the significant adverse events in available clinical trial safety data or in postmarketing pharmacovigilance analyses. This case highlights a new severe hemorrhagic complication that can cause permanent visual damage related to faricimab even in well-monitored patients.
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