Bridging Mammography and Lung Cancer Screening: Eligibility, Uptake and Potential Impact
Ali Ajrouch1, Yara Khalifeh2, Amir F Beirat2
1Department of Family Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Cancer Medicine
|January 20, 2026
Summary
Integrating lung cancer screening (LCS) with mammography could improve early detection, as many eligible women undergo mammograms but not LCS. This approach particularly benefits rural women, addressing disparities in screening uptake.
Area of Science:
- Oncology
- Public Health
- Radiology
Background:
- Lung cancer (LC) is the leading cause of cancer death in women.
- Lung cancer screening (LCS) uptake is significantly lower than mammography screening.
- Leveraging mammography programs could potentially increase LCS uptake.
Purpose of the Study:
- Determine the proportion of women with LC eligible for both mammography and LCS.
- Assess the potential for earlier LC detection through integrated screening.
- Identify factors influencing screening uptake among dually eligible women.
Main Methods:
- Retrospective cross-sectional study of 345 women with newly diagnosed LC.
- Assessed eligibility for LCS (USPSTF 2013/2021) and mammography (2016).
- Analyzed sociodemographic factors associated with screening uptake in dually eligible women.
Main Results:
- 43.5%-49.3% of women were eligible for LCS, while 73.3% were eligible for mammography.
- Mammography uptake (41.5%) far exceeded LCS uptake (13.9%).
- Dual eligibility was found in 45.2% of cases; 41.2% of LCS-eligible women received mammography.
- Rural residency was linked to lower LCS uptake (OR 0.42), while mammography receipt was linked to higher LCS uptake (OR 2.67).
Conclusions:
- Many LCS-eligible women undergo mammography, indicating a missed opportunity for earlier LC detection.
- Integrating LCS with mammography programs could enhance early lung cancer diagnosis.
- This integrated approach may help reduce screening disparities, particularly for rural populations.
Keywords:
health disparitieslung cancerlung cancer screeningmammographymarket viability assessmentwomen’s healthMore Related Videos
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