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Updated: Jan 22, 2026

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Claudication and Hypertension From Aortic Occlusion in Takayasu Arteritis: Revascularization With Excimer Laser and

Sicheng Yao1, Xiao Di1, Yuexin Chen1

  • 1Department of Vascular Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.

Vascular and Endovascular Surgery
|January 20, 2026
PubMed

Insights

This study shows that combining excimer laser atherectomy (ELA) with drug-eluting stents (DES) effectively treats complex aortic blockages in Takayasu arteritis (TA). The minimally invasive approach improved patient health and maintained artery openness long-term.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Vascular Surgery

Background:

  • Takayasu arteritis (TA) can cause complex aortic occlusions, leading to severe hypertension and limb claudication.
  • Minimally invasive endovascular techniques are preferred for young patients to avoid open surgery risks.

Purpose of the Study:

  • To assess the efficacy of a multimodal endovascular strategy using excimer laser atherectomy (ELA), percutaneous transluminal angioplasty (PTA), and drug-eluting stent (DES) for complex aortic occlusion in TA.

Main Methods:

  • A 24-year-old female with TA and severe symptoms underwent a sequential endovascular procedure.
  • Excimer laser atherectomy (ELA) was used for debulking the occlusion, followed by PTA and DES implantation to prevent restenosis.

Main Results:

  • At 6-month follow-up, patients showed improved ankle-brachial indices and normalized blood pressure, with resolution of claudication.
  • Post-procedure CTA confirmed sustained aortic artery patency and no restenosis or collateralization.

Conclusions:

  • Integrating ELA and DES is a feasible and effective minimally invasive strategy for managing TA-related aortic lesions.
  • This approach achieves durable hemodynamic and clinical improvements in patients with complex aortic occlusions.

Keywords:
Takayasu arteritisdrug-eluting stentexcimer laser atherectomy

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