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Virtual reality and perioperative anxiety: a randomized controlled trial
Mouna Ouaz1, Zayati Mohamed1, Khalifa Issam2
1Anesthesia and Intensive Care Departement of Mahdia University Hospital, Mahdia, Tunisia.
The Libyan Journal of Medicine
|January 20, 2026
Summary
Virtual reality (VR) significantly reduced intraoperative anxiolytic use in patients undergoing regional anesthesia. While VR did not alter preoperative anxiety, it effectively managed perioperative anxiety and may prevent postoperative complications.
Area of Science:
- Anesthesiology and Perioperative Medicine
- Medical Technology and Innovation
- Psychological Health in Healthcare
Background:
- Preoperative anxiety is a common patient concern impacting surgical outcomes.
- Virtual reality (VR) offers a promising non-pharmacological approach for anxiety and pain management.
- Managing perioperative anxiety is crucial for optimal anesthetic care and patient recovery.
Purpose of the Study:
- To evaluate the impact of virtual reality on perioperative anxiety in patients undergoing regional anesthesia.
- To assess the effect of VR on intraoperative anxiolytic consumption and patient satisfaction.
- To determine VR's role in preventing postoperative anxiety and complications.
Main Methods:
- A monocentric, prospective, randomized study involving 72 patients scheduled for orthopedic surgery.
- Patients were allocated to either a VR group (n=36) or a control group (n=36).
- Anxiety levels (STAI-6, LIKERT), anxiolytic use (Midazolam), and patient satisfaction were measured.
Main Results:
- No significant difference in preoperative anxiety levels between VR and control groups (STAI-6 scores: 43.2 vs. 44.8).
- Intraoperative anxiolytic use was substantially lower in the VR group (5.8%) compared to the control group (61.7%, p < 0.001).
- Postoperative anxiety reduction and patient satisfaction were comparable between groups.
Conclusions:
- Virtual reality is an effective tool for reducing anxiolytic medication needs during regional anesthesia.
- VR can help manage perioperative anxiety, potentially mitigating postoperative complications.
- VR integration into anesthetic care shows promise for enhancing patient comfort and safety.
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