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Updated: Jan 22, 2026

Ileectomy-induced Bile Overaccumulation in Mouse Intestine
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Evaluating the Impact of Intestinal Bile Salts on Drug Absorption Using PBPK Modeling: Case Studies With Efavirenz,

Laura G Al-Amiry Santos1, Sebastian Polak1,2, Karen Rowland Yeo1

  • 1Certara UK Limited, Sheffield, UK.

CPT: Pharmacometrics & Systems Pharmacology
|January 20, 2026
PubMed

Keywords:
PBPK modelingdrug absorptionintestinal bile saltspharmacokineticssensitivity analysis

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