Related Experiment Video
Updated: Jan 22, 2026
11:35
Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
Published on: December 8, 2010
16.9K
A Motor-Integrated Three-Dimensional Covalent Organic Framework with Dual-Mode Functionality.
Junxia Ren1, Yujie Wang2,3, Jinquan Suo1
1State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Jilin University, Changchun 130012, P. R. China.
Journal of the American Chemical Society
|January 20, 2026
Summary
Researchers created a new material by embedding molecular motors into covalent organic frameworks (COFs). This innovation enables light-controlled carbon dioxide capture and drug delivery, bridging molecular motion to macroscopic functions.
Area of Science:
- Materials Science
- Supramolecular Chemistry
- Nanotechnology
Background:
- Biological systems utilize molecular machines within scaffolds for macroscopic functions.
- Synthetic replication requires integrating molecular motors into dynamic, ordered frameworks.
Purpose of the Study:
- To develop a reticular design strategy for incorporating overcrowded alkene rotary motors into 3D covalent organic frameworks (COFs).
- To create a prototype material (JUC-666) demonstrating coordinated molecular motion and macroscopic functionality.
Main Methods:
- Reticular synthesis of 3D covalent organic frameworks (COFs) incorporating overcrowded alkene rotary motors.
- Spectroscopic and kinetic analyses to confirm unidirectional motor rotation in solution and solid states.
- Evaluation of CO2 uptake modulation and light-controlled drug release functionalities.
Main Results:
- Successful incorporation of rotary motors into a 3D COF (JUC-666) exhibiting unidirectional rotation.
- Demonstrated reversible CO2 uptake modulation (>83% capacity variation at 273 K) via light-dark cycling.
- Achieved precisely controlled drug release with light-dosage-proportional kinetics (∼50-fold increase in cumulative release).
Conclusions:
- Covalent organic frameworks (COFs) can effectively bridge molecular-scale motion to macroscopic responses.
- JUC-666 serves as a platform for designing adaptive functional materials with dual-mode capabilities.
- This approach enables the development of materials responsive to external stimuli like light.
More Related Videos
Related Concept Videos
02:18Network Covalent Solids
16.1K
Network covalent solids contain a three-dimensional network of covalently bonded atoms as found in the crystal structures of nonmetals like diamond, graphite, silicon, and some covalent compounds, such as silicon dioxide (sand) and silicon carbide (carborundum, the abrasive on sandpaper). Many minerals have networks of covalent bonds.
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
16.1K
01:29Covalent Bonds
160.3K
Overview
160.3K
01:08Covalent Bonds
10.0K
Overview
When two atoms share electrons to complete their valence shells, they create a covalent bond. An atom's electronegativity—the force with which shared electrons are pulled towards an atom—determines how the electrons are shared. Molecules formed with covalent bonds can be either polar or nonpolar. Atoms with similar electronegativities form nonpolar covalent bonds; the electrons are shared equally. Atoms with different electronegativities share electrons unequally,...
When two atoms share electrons to complete their valence shells, they create a covalent bond. An atom's electronegativity—the force with which shared electrons are pulled towards an atom—determines how the electrons are shared. Molecules formed with covalent bonds can be either polar or nonpolar. Atoms with similar electronegativities form nonpolar covalent bonds; the electrons are shared equally. Atoms with different electronegativities share electrons unequally,...
10.0K
02:04Covalently Linked Protein Regulators
8.7K
Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
These groups modify specific amino acids in a protein....
These groups modify specific amino acids in a protein....
8.7K
02:46Covalent Bonding and Lewis Structures
60.7K
Compared to ionic bonds, which results from the transfer of electrons between metallic and nonmetallic atoms, covalent bonds result from the mutual attraction of atoms for a “shared” pair of electrons.
60.7K
01:07What is a Mode?
25.1K
The mode is one of the commonly used measures of a central tendency. It is defined as the most frequent value in a data set.
There can be more than one mode in a data set if multiple values have the same highest frequency. For instance, suppose that the Statistics exam scores of 20 students are: 50; 53; 59; 59; 63; 63; 72; 72; 72; 72; 72; 76; 78; 81; 83; 84; 84; 84; 90; 93. Here, the mode is 72, as it occurs most frequently, five times.
A data set with two modes is called bimodal. For example,...
There can be more than one mode in a data set if multiple values have the same highest frequency. For instance, suppose that the Statistics exam scores of 20 students are: 50; 53; 59; 59; 63; 63; 72; 72; 72; 72; 72; 76; 78; 81; 83; 84; 84; 84; 90; 93. Here, the mode is 72, as it occurs most frequently, five times.
A data set with two modes is called bimodal. For example,...
25.1K