Dengue in children and adolescents with onco-hematological disease: a case series

Dengue is a viral disease transmitted mainly by the Aedes aegypti mosquito. Argentina has seen a significant increase in epidemics in recent years. Pediatric patients with oncohematological diseases are particularly vulnerable due to their immunosuppression, which can predispose them to severe cases. This report presents five clinical cases of pediatric patients with oncohematological diseases who developed dengue infection, illustrating the variability in its clinical presentation. Symptoms were heterogeneous, ranging from mild forms to severe cases with liver failure, bleeding, and the need for intensive care. Early identification, close monitoring, and an interdisciplinary approach are key to management. This series of cases reinforces the need for active clinical surveillance for fever in an epidemiological context, even in the absence of typical symptoms.