Related Experiment Video
Updated: Jun 28, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
Evaluation of Left Ventricular, Left Atrial, and Right Ventricular Function in Patients With Behçet's Disease by
Mucahit Tan1, Rumeysa Bilmez Tan2, Yuksel Kaya1
1Department of Cardiology, Yuzuncu Yil University Faculty of Medicine, Van, Turkey.
Insights
Behçet
Area of Science:
- Cardiology
- Rheumatology
- Medical Imaging
Background:
- Behçet's disease (BD) is associated with diverse cardiovascular complications.
- Strain echocardiography is valuable for detecting subclinical cardiac dysfunction.
Purpose of the Study:
- To assess left ventricular (LV), left atrium (LA), and right ventricular (RV) function in BD patients using strain echocardiography.
- To evaluate cardiac involvement in Behçet's disease.
Main Methods:
- Compared 27 BD patients with 34 healthy controls.
- Utilized strain echocardiography to assess LV, LA, and RV function.
- Recorded basic echocardiographic parameters and medical histories.
Main Results:
- No significant differences in LV or RV global longitudinal strain between groups.
- Significantly reduced left atrial reservoir strain (LASr) in BD patients (p = 0.035).
- No significant differences in strain parameters when comparing BD patients with and without uveitis.
Conclusions:
- Behçet's disease does not appear to impair LV or RV function.
- LA mechanical function is demonstrably impaired in BD patients.
- Strain echocardiography reveals specific cardiac functional deficits in Behçet's disease.
Purpose:
Behçet's disease (BD) can lead to a wide spectrum of cardiovascular manifestations. Strain echocardiography has emerged as a prominent modality in clinical practice owing to its significant prognostic value and ability to detect subclinical cardiac involvement in various cardiovascular diseases. This study was designed to evaluate left ventricular (LV), left atrium (LA), and right ventricular (RV) function in BD patients using strain echocardiography.
Methods:
A total of 61 participants were included in the study, comprising 27 patients with BD and 34 healthy controls. After medical histories and cardiac symptoms were obtained from all participants, basic echocardiographic parameters were recorded, and LV, LA, and RV functions were assessed using strain echocardiography.
Results:
No significant differences were observed between the two groups in terms of cardiac chamber dimensions and diastolic parameters. No significant difference was observed in global longitudinal strain values between the BD and control groups (p = 0.078). Similarly, no significant differences were found in right ventricular strain values. Regarding LA strain (LAS) parameters, LASr was found to be significantly lower in the BD group compared with the control group (p = 0.035). In the subgroup analysis comparing BD patients with and without uveitis, there were no statistically significant differences in LASr (p = 0.813), LAScd (p = 0.963), or LASct (p = 0.911).
Conclusion:
In conclusion, our study did not show any deterioration in LV or RV function in BD, but it did show deterioration in LA mechanical function.
Related Concept Videos
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
Mitral Stenosis II: Clinical features and Diagnostic Tests
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Dysrhythmias V: Evaluating Dysrhythmias
Cardiomyopathy III: Hypertrophic Cardiomyopathy

