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Updated: Jan 22, 2026

Characterization of Membrane Transporters by Heterologous Expression in E. coli and Production of Membrane Vesicles
Published on: December 31, 2019
Classification and biogenesis of vesicles, and their roles in the transport of viral components
Wenchao Liu1, Junting Xu1, Guohui Li1
1Department of Biological Sciences, School of Life Sciences, Jiangsu University, 212013, Jiangsu, Zhenjiang, China.
Abstract:
Vesicles are a class of naturally released, cell-derived, lipid bilayer enclosed compartments. Different kinds of vesicles can be produced within cells. Cellular processes are heavily dependent on the synergistic action of some vesicles within cells. Studies have showed diverse roles of vesicles including intracellular trafficking, cell-to-cell communication and intracellular digestion. Vesicles can deliver not only some proteins and lipids to target sites but also viral components between nucleus and cytoplasm. Transmembrane transport of some viral nucleocapsids through intranuclear microvesicle is necessary for some viral propagation in host. Viral infection and viral spread are directly involved with vesicle-mediated endocytosis and exocytosis. So, the production of some progeny virion and viral release can be regulated by vesicle-mediated cellular transport and exocytosis. In the study, the classification, biogenesis and function of vesicles were summarized to better understand their role in viral propagation. In conclusion, vesicular trafficking can play important roles in regulation of viral entry, transport of viral substance and viral spread.
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