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Related Experiment Video

Updated: Jan 22, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

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Systemic Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer: ASCO Living Guideline, Version

Mary-Ellen Taplin¹, Irbaz Bin Riaz², R Bryan Rumble³

¹Dana-Farber Cancer Institute, Boston, MA.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology

|January 20, 2026

Summary

This summary is machine-generated.

Living guidelines provide updated clinical practice recommendations for rapidly evolving medical topics. These guidelines are regularly reviewed by expert panels to ensure current evidence informs patient care.

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Area of Science:

Oncology
Clinical Practice Guidelines

Background:

Medical knowledge and evidence evolve rapidly.
Clinical practice guidelines require frequent updates to reflect new evidence.

Purpose of the Study:

To describe the methodology and framework for ASCO Living Guidelines.
To explain the process of continuous literature review and guideline updates.

Main Methods:

Systematic review of health literature on a continuous basis.
Regular updates by a standing expert panel.
Adherence to ASCO Guidelines Methodology Manual and Conflict of Interest Policy.

Main Results:

Living guidelines ensure recommendations are based on the most current evidence.
Regularly scheduled updates are published to inform clinical practice.
Guidelines are available at www.asco.org/genitourinary-cancer-guidelines.

Conclusions:

Living guidelines are essential for areas with rapidly changing evidence.
These guidelines support, but do not replace, clinical judgment.
Continuous updates ensure timely integration of new research into patient care.