Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Function Tests01:25

Pulmonary Function Tests

767
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
767
Requirements for Human Life01:26

Requirements for Human Life

13.1K
The Earth and its atmosphere have provided humans with air, water, and food, but these are not the only requirements for survival. Humans also require a specific range of temperature and pressure that the Earth and its atmosphere provides.
Oxygen
Atmospheric air is only about 20 percent oxygen, but that oxygen is a key component of the chemical reactions that keep the body alive, including the reactions that produce ATP. Brain cells are susceptible to a lack of oxygen because they require a...
13.1K
Design Consideration01:22

Design Consideration

557
Designing a structure involves a series of considerations, primarily the material's ultimate strength, calculated through tests that measure changes under increased force until the material reaches its breaking point or limit. The ultimate load, where the material breaks, is divided by its original cross-sectional area, resulting in the ultimate normal stress or strength. The ultimate shearing stress is another significant factor taken into account.
The factor of safety is another key...
557
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

922
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
922
Serum Studies: Renal Function Tests01:24

Serum Studies: Renal Function Tests

382
Renal function tests are crucial for assessing kidney health, monitoring disease progression, and evaluating the kidneys' efficiency in waste elimination, fluid balance, and electrolyte regulation. These tests offer critical insights into kidney function, even though routine measurements may appear normal until there is a significant decline in the glomerular filtration rate or GFR. Typically, signs of kidney impairment only become evident when the GFR falls to about 50% of its normal level.
382
Nursing Implementation01:15

Nursing Implementation

6.0K
Implementation is the execution of the nursing care plan developed during the planning phase.
The five steps to implementing effective nursing care include reassessing the patient, reviewing and revising the existing nursing care plan, organizing the resources and care delivery, anticipating and preventing complications, and implementing nursing interventions.
6.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical Impact of the BIOFIRE® FILMARRAY® Pneumonia Panel in the Veterans Affairs Healthcare System: A Difference-in-Differences Study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

Planning for the future of the American Society for Microbiology's Health Unit by the Council on Microbial Sciences.

mSphere·2026
Same author

Comparison of the VITEK REVEAL AST and Accelerate Pheno systems for fast antimicrobial susceptibility testing of gram-negative blood cultures at a large academic health system.

Journal of clinical microbiology·2025
Same author

Navigating and Advancing Market Access for In Vitro Diagnostics: Understanding the Roles of Key Stakeholders and Policy.

Open forum infectious diseases·2025
Same author

Beyond Accuracy: Methodological Advances for Assessing the Clinical Impact of Infectious Disease Diagnostics.

Open forum infectious diseases·2025
Same author

Multiplex PCR panel dynamics: implications for therapy duration and methodological considerations.

Critical care (London, England)·2025

Related Experiment Video

Updated: Jan 22, 2026

Antimicrobial Susceptibility Testing of Mycobacterium Tuberculosis Complex for First and Second Line Drugs by Broth Dilution in a Microtiter Plate Format
12:39

Antimicrobial Susceptibility Testing of Mycobacterium Tuberculosis Complex for First and Second Line Drugs by Broth Dilution in a Microtiter Plate Format

Published on: June 24, 2011

38.8K

Real-world laboratory functionality requirements and implementation considerations for fast phenotypic antimicrobial

Patrick M McDaneld1, Theresa Okeyo Owuor2, Shivaramu Keelara2

  • 1bioMérieux, US Medical Affairs, Salt Lake City, USA.

Diagnostic Microbiology and Infectious Disease
|January 20, 2026
PubMed
Summary

Fast phenotypic antimicrobial susceptibility testing (fAST) can improve bacteremia management. Successful implementation requires addressing lab barriers, engaging stakeholders, and evaluating outcomes.

Keywords:
Antimicrobial susceptibility testingBloodstream infectionClinical MicrobiologyImplementationRapid Diagnostics

More Related Videos

Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium
12:08

Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium

Published on: February 14, 2022

3.3K
Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
10:16

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World

Published on: April 7, 2020

9.0K

Related Experiment Videos

Last Updated: Jan 22, 2026

Antimicrobial Susceptibility Testing of Mycobacterium Tuberculosis Complex for First and Second Line Drugs by Broth Dilution in a Microtiter Plate Format
12:39

Antimicrobial Susceptibility Testing of Mycobacterium Tuberculosis Complex for First and Second Line Drugs by Broth Dilution in a Microtiter Plate Format

Published on: June 24, 2011

38.8K
Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium
12:08

Rapid Antimicrobial Susceptibility Testing by Stimulated Raman Scattering Imaging of Deuterium Incorporation in a Single Bacterium

Published on: February 14, 2022

3.3K
Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
10:16

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World

Published on: April 7, 2020

9.0K

Area of Science:

  • Clinical Microbiology
  • Diagnostic Technology Evaluation
  • Health Services Research

Background:

  • Effective antimicrobial therapy is crucial for managing bacteremia, reducing patient morbidity and mortality.
  • Fast phenotypic antimicrobial susceptibility testing (fAST) promises accelerated results for optimal treatment selection.
  • Real-world fAST adoption faces challenges related to lab infrastructure, stewardship, and platform adaptability.

Purpose of the Study:

  • To assess the performance and user experience of the VITEK® REVEAL™ system in an Early Evaluation Program (EEP).
  • To qualitatively evaluate barriers and facilitators to fAST implementation in hospital microbiology labs.
  • To identify key determinants and strategies for successful fAST adoption.

Main Methods:

  • An Early Evaluation Program (EEP) involving 13 U.S. hospital laboratories using the VITEK® REVEAL™ system.
  • A survey component within the EEP to gather qualitative data on user perceptions, barriers, and facilitators.
  • Analysis of survey responses mapped to the Consolidated Framework for Implementation Research (CFIR).

Main Results:

  • Ease of use, faster turnaround times, and clinical impact were highly valued fAST features.
  • High willingness to adopt fAST was tempered by concerns about evidence gaps, resources, and performance data.
  • Patient complexity, lab staffing, and workflow integration significantly influenced adoption decisions.

Conclusions:

  • fAST has the potential to significantly improve bacteremia management.
  • Successful implementation hinges on addressing laboratory-specific barriers, fostering collaboration, and continuous outcome evaluation.
  • Strategies like stakeholder engagement and tailored software are critical for overcoming adoption hurdles.