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Updated: Jan 22, 2026

Author Spotlight: Unveiling Cellular Functions and Potential Clinical Implications of Leptomeningeal Lymphatic Endothelial Cells
Published on: September 8, 2023
A Granular Cell Variant of Adult Primary Leptomeningeal Gliomatosis Mimicking a Granulomatous Process: A Case Report
Nelson José Vera Brito1, Álvaro Bonelli Franco2, Cristina Arévalo Martin3
1Department of Pathology, Hospital Universitario Rey Juan Carlos, Móstoles, Spain.
Abstract:
We report the case of a 77-year-old patient with glioblastoma, IDH-wildtype, presenting as adult primary leptomeningeal gliomatosis with granular cell morphology in the biopsy. The clinico-radiological presentation initially suggested a non-neoplastic granulomatous process. Comprehensive molecular studies and post-mortem examination were subsequently performed.
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