Ultrasound-Based Prediction Model for Air Enema Failure in Pediatric Ileocolic Intussusception: Comparison of

Sung-Ha Kim1, Jae-Hyun Kwon, So-Hyun Paek

  • 1Department of Emergency Medicine, Bundang CHA Medical Center, CHA University, Seongnam-si, South Korea.

Pediatric Emergency Care
|January 20, 2026
PubMed

Insights

Ultrasound features can predict failed intussusception reduction in children. A validated model using specific ultrasonographic findings improves prediction and supports point-of-care ultrasound (POCUS) use in pediatric emergencies.

Area of Science:

  • Pediatric Radiology
  • Emergency Medicine
  • Gastroenterology

Background:

  • Pediatric ileocolic intussusception diagnosis is challenging due to atypical presentations.
  • Enema reduction is standard, but failure necessitates surgery.
  • Identifying predictors of reduction failure is crucial for timely intervention.

Purpose of the Study:

  • Identify ultrasonographic predictors of enema reduction failure in pediatric intussusception.
  • Develop and validate a predictive model for reduction failure.
  • Assess the utility of point-of-care ultrasound (POCUS) in this context.

Main Methods:

  • Retrospective study of children undergoing air enema reduction for intussusception.
  • Logistic regression analysis to identify predictors of reduction failure.
  • Model validation and comparative analysis of radiologist-performed ultrasound versus POCUS.

Main Results:

  • Lymph nodes, invagination length, hypoechoic ring thickness, and low vascularity on ultrasound predicted failure.
  • A 6-feature ultrasound model showed good predictive performance and 100% sensitivity upon validation.
  • Radiologists identified risk features more comprehensively than pediatric emergency physicians using POCUS.

Conclusions:

  • Ultrasound features are reliable predictors of enema reduction failure in pediatric intussusception.
  • A validated predictive model enhances management decisions.
  • Standardized ultrasound assessment and expanded POCUS roles are recommended for pediatric emergencies.
Abstract

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