A case report of venous air embolism induced by bone marrow cavity irrigation

Boe Feng1, Hong Duan1, Kai Liu2

  • 1Department of Anesthesiology, Kunming Children's Hospital & Children's Hospital of Kunming Medical University, Kunming, China.

Medicine
|January 21, 2026
PubMed

Insights

Severe venous air embolism (VAE) occurred during pediatric bone marrow irrigation. Prompt intervention including catheter aspiration and oxygen therapy led to full recovery, highlighting the need for vigilance in orthopedic surgery.

Area of Science:

  • Pediatric Orthopedic Surgery
  • Anesthesiology
  • Critical Care Medicine

Background:

  • Venous air embolism (VAE) is a rare yet life-threatening complication during surgical procedures involving vascular structures or pressurized irrigation.
  • Pediatric patients undergoing orthopedic surgery are susceptible to VAE, particularly during procedures like bone marrow cavity irrigation.

Purpose of the Study:

  • To report a rare case of severe VAE in a pediatric patient during femoral osteomyelitis surgery.
  • To emphasize the importance of prompt diagnosis and management of VAE in pediatric orthopedic procedures.

Main Methods:

  • A 3-year-old girl with femoral osteomyelitis underwent surgery involving bone marrow cavity irrigation.
  • The patient developed rapid clinical deterioration indicative of VAE.
  • Diagnosis was confirmed via bedside echocardiogram, and emergency interventions were initiated.

Main Results:

  • The patient experienced sudden drops in end-tidal carbon dioxide, oxygen saturation, pulse rate, and blood pressure.
  • Interventions including catheter aspiration, 100% oxygen, left lateral positioning, and cessation of irrigation rapidly resolved symptoms.
  • The patient recovered fully without neurological deficits.

Conclusions:

  • This case underscores the critical need for heightened vigilance during pediatric orthopedic procedures involving potential air introduction.
  • Immediate echocardiographic assessment is crucial for rapid VAE diagnosis.
  • Timely and appropriate emergency interventions are vital to prevent morbidity and mortality associated with VAE in children.

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