Related Experiment Video
Updated: Jan 22, 2026

08:04
Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro
Published on: March 18, 2014
13.2K
Molecular guided therapy leading to exceptional response in relapsed osteosarcoma
Elizabeth Wert1,2, Leah Menachery2, Jeremy Hengst2
1The University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Frontiers in Pharmacology
|January 21, 2026
Summary
Molecularly guided therapy identified a novel drug combination for refractory metastatic osteosarcoma. This personalized approach led to a complete response and long-term survival in a pediatric patient with advanced bone cancer.
Area of Science:
- Oncology
- Genomics
- Pharmacology
Background:
- Osteosarcoma is a challenging pediatric bone cancer, particularly with metastatic disease.
- Metastatic osteosarcoma often shows resistance to conventional therapies.
- Novel treatment strategies are crucial for improving outcomes in refractory cases.
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