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Related Experiment Video

Updated: Jan 22, 2026

Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications

Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications

Published on: May 31, 2018

Biomaterial-assisted neuralization strategies for tissue engineering applications.

Jiahao Ye^1,2, Lei Ji³, Liangle Liu¹

¹The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325200, China.

Materials Today. Bio

|January 21, 2026

Summary

Biomaterials can enhance tissue repair by aiding neuralization, which involves modulating the nervous system. This review explores how smart biomaterials improve functional recovery in regenerative medicine.

Keywords:

Biomaterials Neuralization Neuromodulation Tissue engineering

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Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling

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Published on: May 31, 2017

Area of Science:

Biomaterials Science
Regenerative Medicine
Neuroscience

Background:

Tissue repair strategies often overlook neuromodulation, hindering functional recovery.
Neuromodulation is critical for integrating regenerated tissues and restoring physiological function.
Biomaterial-based approaches are emerging to address this gap in regenerative medicine.

Purpose of the Study:

To comprehensively analyze biomaterial-assisted neuralization for tissue repair.
To elucidate the mechanisms of neuralized tissue repair.
To highlight advances and future directions in biomaterial-assisted neuralization for tissue engineering.

Main Methods:

Review of biomaterial-assisted neuralization mechanisms, including neural response, inflammation, neurovascular coupling, and stem cell behavior.
Analysis of smart-responsive and electroactive biomaterials in neuralization.
Examination of strategies for structural/mechanical support, delivery systems, microenvironment construction, and responsive biomaterials.

Main Results:

Smart-responsive and electroactive biomaterials facilitate neuralization and improve functional integration.
Biomaterials can be designed to establish conducive foundations, deliver modulators, regulate electrophysiology, and respond intelligently.
Understanding neural responses, inflammation, neurovascular coupling, and stem cell modulation is key.

Conclusions:

Biomaterial-assisted neuralization is a promising strategy for advancing regenerative medicine.
Next-generation biomaterials require innovative designs focusing on neuromodulation for enhanced tissue regeneration.
Further research into smart biomaterials and their integration with neural pathways will improve functional recovery.