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Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
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Social survey on knowledge, attitude and practice of hypertrophic cardiomyopathy

Weidong Lan1, Bitong He2, Sailing Hu2

  • 1Department of Rehabilitation Medicine, The First People's Hospital of Xiaoshan District, Xiaoshan Affiliated Hospital of Wenzhou Medical University, Xiaoshan, China.

Frontiers in Cardiovascular Medicine
|January 21, 2026
PubMed

Insights

Patients with hypertrophic cardiomyopathy (HCM) show deficits in rehabilitation knowledge, attitudes, and behaviors. Factors like education and income significantly influence these areas, necessitating targeted interventions for improved quality of life.

Area of Science:

  • Cardiology
  • Patient Rehabilitation
  • Health Psychology

Background:

  • Hypertrophic cardiomyopathy (HCM) requires comprehensive rehabilitation.
  • Understanding patient knowledge, attitudes, and behaviors is crucial for effective rehabilitation.
  • Existing rehabilitation strategies may not fully address patient-specific needs.

Purpose of the Study:

  • To evaluate the knowledge, attitudes, and behaviors of patients with hypertrophic cardiomyopathy during rehabilitation.
  • To identify key factors influencing these aspects in HCM patients.
  • To inform the development of optimized rehabilitation interventions.

Main Methods:

  • A cross-sectional study involving 193 HCM patients.
  • Utilized a specialized questionnaire assessing rehabilitation knowledge, attitude, and behavior.
  • Employed univariate and multivariate regression analyses to determine influencing factors.

Main Results:

  • Patients scored 7.91±3.14 in knowledge, 34.73±3.16 in attitude, and 39.44±3.95 in behavior.
  • Overall score was 82.08±7.84.
  • Education level, employment status, and income significantly impacted knowledge, attitudes, and behaviors (P<0.05).

Conclusions:

  • Significant room for improvement exists in HCM patient rehabilitation knowledge, attitudes, and behaviors.
  • Interventions should be tailored based on individual patient profiles and influencing factors.
  • Optimizing rehabilitation cognition, attitude, and behavior can enhance patient quality of life.
Abstract

Keywords:
attitudebehaviorhypertrophic cardiomyopathyknowledgesocial survey

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