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Work Reintegration After Chemotherapy in Patients With Early-Stage Breast Cancer: The RESTART Cross-Sectional Survey.

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Return to work for breast cancer survivors is challenging due to treatment side effects. Lower education and physically demanding jobs hinder return, highlighting the need for integrated survivorship care and vocational support.

Keywords:
breast canceroccupational healthquality of lifereturn to worksurvivorship

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Area of Science:

  • Oncology
  • Occupational Health
  • Psychosocial Medicine

Background:

  • Return to work (RTW) is crucial for breast cancer survivors' financial, personal, and social recovery.
  • Treatment sequelae (physical, cognitive, emotional) often impede this transition.
  • This study investigated RTW outcomes and associated factors in early-stage breast cancer survivors treated with chemotherapy.

Purpose of the Study:

  • To evaluate return-to-work outcomes in breast cancer survivors.
  • To identify clinical, psychosocial, and occupational factors linked to sick leave and prolonged work absence.

Main Methods:

  • Cross-sectional study in Portugal of professionally active women (≤60 years) ≥12 months post-chemotherapy.
  • Data collected via medical records and questionnaires (sociodemographic, clinical, employment).
  • Quality of life assessed using EORTC QLQ-BR23; multivariable logistic regression used for analysis.

Main Results:

  • 83.1% took sick leave, 71.2% continued leave post-chemotherapy; 81.4% eventually returned to work.
  • Common reasons for continued leave: fatigue, cognitive impairment, mood changes, inadequate workplace adaptation.
  • Lower education and higher physical job demands were associated with persistent leave; anti-HER2 therapy showed a borderline association.
  • Women on leave reported worse quality of life, especially regarding body image and breast/arm symptoms.

Conclusions:

  • Return to work post-breast cancer is multifactorial, involving medical, occupational, and psychosocial elements.
  • Portuguese survivors faced significant work disruption, emphasizing the need for integrated survivorship care and vocational support.
  • Interventions should target symptom management, employer collaboration, and work capacity assessment for successful reintegration.