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Clinical analysis of laparoscopic pyeloplsty for ureteropelvic junction obstruction in infants under 3 months old

Zedong Bian1, Geng Xiong1, Tong Liu1

  • 1Department of Pediatric Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.

Frontiers in Pediatrics
|January 21, 2026
PubMed

Insights

Laparoscopic pyeloplasty (LP) is safe and effective for infants with ureteropelvic junction obstruction (UPJO). This minimally invasive procedure shows excellent outcomes in infants under three months, with no significant differences compared to older infants.

Area of Science:

  • Pediatric Urology
  • Minimally Invasive Surgery
  • Neonatal Surgery

Background:

  • Ureteropelvic junction obstruction (UPJO) is a common cause of congenital hydronephrosis in infants.
  • Surgical intervention is often required to relieve the obstruction and preserve renal function.
  • Laparoscopic pyeloplasty (LP) has emerged as a viable alternative to open surgery.

Purpose of the Study:

  • To evaluate the safety and efficacy of laparoscopic pyeloplasty (LP) for treating ureteropelvic junction obstruction (UPJO) in infants under 3 months of age.
  • To compare outcomes in infants aged 0-3 months with those aged 4-12 months.

Main Methods:

  • Retrospective analysis of 45 infants with UPJO treated with LP.
  • Patients divided into two groups: 0-3 months (Group A, n=25) and 4-12 months (Group B, n=20).
  • Comparison of operative time, hospital stay, complications, renal pelvic diameter (APD), and minimum renal cortex thickness (Min.RCT).

Main Results:

  • All LP procedures were completed successfully without conversion to open surgery.
  • No significant differences in operative time, hospital stay, complication rates, or postoperative APD/Min.RCT between groups.
  • Both groups demonstrated significant improvement in APD reduction and Min.RCT increase post-surgery.
  • No recurrence or reoperation required during a median follow-up of 38.65 months.

Conclusions:

  • Laparoscopic pyeloplasty (LP) is a safe and effective treatment for UPJO in infants ≤3 months.
  • The procedure offers comparable outcomes to older infants, supporting its use in younger neonates.
  • LP is a recommended surgical option for UPJO in infants requiring intervention.
Abstract

Keywords:
infantlaparoscopypyeloplastysurgeryureteropelvic junction obstruction

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