Related Experiment Video

Updated: Jul 21, 2026

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood
08:20

Measuring Neural Mechanisms Underlying Sleep-Dependent Memory Consolidation During Naps in Early Childhood

Published on: October 2, 2019

The association between Children's sleep quality and juvenile idiopathic arthritis

Linxia Li1, Yazhen Di2, Zhanli Liu1

  • 1Department of Neurology, Hangzhou Children's Hospital, Hangzhou City, Zhejiang Province, China.

Frontiers in Pediatrics
|January 21, 2026
PubMed

Insights

Children with juvenile idiopathic arthritis (JIA) experience significantly more sleep disturbances than healthy children. These issues are linked to disease activity, functional limitations, and treatments for JIA.

Area of Science:

  • Pediatric Rheumatology
  • Sleep Medicine
  • Clinical Investigation

Background:

  • Juvenile idiopathic arthritis (JIA) is a chronic condition affecting children, with potential impacts on overall well-being.
  • Sleep disturbances are common in pediatric chronic illnesses but understudied in JIA.
  • Understanding sleep issues in JIA is crucial for comprehensive patient care.

Purpose of the Study:

  • To investigate the prevalence and characteristics of sleep disturbances in children diagnosed with JIA.
  • To explore the relationship between sleep quality and disease activity, pain, fatigue, and quality of life in JIA patients.

Main Methods:

  • A case-control study comparing 48 JIA patients with 90 healthy controls.
  • Utilized validated questionnaires including the Children's Sleep Habits Questionnaire (CSHQ) and Sleep Disturbance Scale for Children (SDSC).
  • Assessed disease activity (JADAS-27), quality of life (CHQ-PF28), pain (VAS), and fatigue (PedsQL-MFS).

Main Results:

  • JIA patients exhibited significantly higher rates of sleep disturbance compared to controls (P < 0.01).
  • Abnormalities in CSHQ and SDSC scores were prevalent, correlating with disease activity, functional status, and medication use.
  • Specific issues included shortened sleep duration, daytime sleepiness, night hyperhidrosis, and arousal disorders.

Conclusions:

  • Children with JIA demonstrate a significantly higher incidence of sleep disorders.
  • Sleep disturbances in JIA are associated with disease activity, functional impairment, and potentially medication side effects.
  • Addressing sleep problems should be an integral part of managing JIA in pediatric patients.
Abstract

Keywords:
functional statusjuvenile idiopathic arthritispediatricsqualityof sleepsleep disturbance

More Related Videos

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder04:33

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain04:50

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

Related Concept Videos

Correlations02:20

Correlations

Correlation means that there is a relationship between two or more variables (such as ice cream consumption and crime), but this relationship does not necessarily imply cause and effect. When two variables are correlated, it simply means that as one variable changes, so does the other. We can measure correlation by calculating a statistic known as a correlation coefficient. A correlation coefficient is a number from -1 to +1 that indicates the strength and direction of the relationship between...
Management of Insomnia01:19

Management of Insomnia

The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
Restless Leg Syndrome and Night Terrors01:27

Restless Leg Syndrome and Night Terrors

Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...