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Updated: Jan 22, 2026

Human Neuroendocrine Tumor Cell Lines as a Three-Dimensional Model for the Study of Human Neuroendocrine Tumor Therapy
Published on: August 14, 2012
Functional pancreatic neuroendocrine tumors predominantly presenting with hypercalcemia: a case report
Jieting Duan1, Yanping Zhu1, Yan Wang2
1Department of Gastroenterology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
Abstract:
Functional pancreatic neuroendocrine tumors (F-PNETs) that secrete parathyroid hormone-related protein (PTHrP) and cause hypercalcemia are extremely rare. This report details a 10-year course of a patient with pancreatic neuroendocrine tumor (PNET) and recurrent life-threatening hypercalcemia. Moreover, it comprehensively describes the evolution and management of hypercalcemia in this case, aiming to offer valuable insights for clinical diagnosis and treatment.
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