Related Experiment Video

Updated: Jan 22, 2026

Classical Short-Delay Eyeblink Conditioning in One-Year-Old Children
07:36

Classical Short-Delay Eyeblink Conditioning in One-Year-Old Children

Published on: September 1, 2018

39.8K

Comparison of Short- vs Long-Course Antibiotic Therapy for Children With Tracheitis Associated With an Artificial

Tracy N Zembles1, Rainer G Gedeit2, Martin K Wakeham2

  • 1Department of Enterprise Safety; Children's Wisconsin, Milwaukee, WI, USA.

Pediatric Pulmonology
|January 21, 2026
PubMed

Insights

Shorter antibiotic courses for tracheitis (5 days) are as effective as longer courses (7+ days). Limiting antibiotic duration does not worsen patient outcomes, supporting shorter treatment durations.

Area of Science:

  • Pediatric critical care medicine
  • Infectious diseases
  • Antimicrobial stewardship

Background:

  • Tracheitis treatment duration is a key area for antimicrobial stewardship.
  • Optimizing antibiotic use is crucial to combat resistance and improve patient outcomes.

Purpose of the Study:

  • To compare outcomes of short-course versus long-course antibiotic therapy for pediatric tracheitis.
  • To evaluate the impact of antibiotic duration on re-treatment, new infections, and mortality.

Main Methods:

  • Retrospective cohort study of pediatric intensive care unit patients with tracheitis requiring antibiotics.
  • Comparison of outcomes between patients receiving ≤6 days (short course) versus ≥7 days (long course) of antibiotics.
  • Analysis of re-treatment rates, new pneumonia, and multi-drug resistant organism development.

Main Results:

  • 95 patients analyzed: 42 (short course, median 5 days) and 53 (long course, median 9 days).
  • No statistically significant difference in composite outcomes (re-treatment/pneumonia) or 30-day mortality between groups.
  • Antibiotic duration did not impact the development of subsequent multi-drug resistant organisms.

Conclusions:

  • Short-course antibiotic therapy (≤6 days) for tracheitis is not associated with worse outcomes compared to longer courses.
  • A 5-day antibiotic duration for pediatric tracheitis is recommended, aligning with antimicrobial stewardship principles.
Abstract

Keywords:
antibioticsdurationinfectionpediatrictracheitis

More Related Videos

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy09:40

Characterization of Functionally Associated miRNAs in Glioblastoma and their Engineering into Artificial Clusters for Gene Therapy

Published on: October 4, 2019

6.0K
Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy07:20

Author Spotlight: Repetitive Transcranial Magnetic Stimulation Combined with Movement Observation in Cerebral Palsy

Published on: August 9, 2024

1.8K

Related Concept Videos

Antibiotic Selection00:57

Antibiotic Selection

Overview
59.5K
The Sense of Self: Reflected Self-Appraisal and Social Comparison02:57

The Sense of Self: Reflected Self-Appraisal and Social Comparison

According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...
55.5K
Suctioning the Oropharyngeal Airway01:25

Suctioning the Oropharyngeal Airway

In preparing for oropharyngeal airway suctioning, a nurse must gather all necessary equipment, including a suction unit with tubing, a prepackaged suction kit, sterile gloves, water or saline for irrigation, a water-soluble lubricant, and additional personal protective equipment (such as a gown, mask, and goggles) to control infections.
After assembling the equipment, the nurse should practice hand hygiene and don appropriate PPE according to infection control guidelines to avoid the...
845
Suctioning the Nasopharyngeal Airway01:29

Suctioning the Nasopharyngeal Airway

Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
3.1K
Multiple Comparison Tests01:13

Multiple Comparison Tests

Multiple comparison test, abbreviated as MCT, is a post hoc analysis generally performed after comparing multiple samples with one or more tests. An MCT will help identify a significantly different sample among multiple samples or a factor among multiple factors.
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
4.4K
Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
1.4K