National Cancer Statistics: American College of Surgeons Cancer Programs Annual Report from 2022 Participant User...

Area of Science:

• Oncology
• Cancer Epidemiology
• Health Services Research

Background:

• The American College of Surgeons Cancer Program's National Cancer Database (NCDB) provides annual reports on cancer statistics.
• The 2022 report utilizes data from the NCDB adult participant user file, focusing on diagnoses, demographics, and treatments.

Purpose of the Study:

• To present updated cancer data from the NCDB 2022 adult participant user file.
• To analyze trends in cancer diagnoses, patient demographics, and treatments.
• To provide in-depth reports on treatment and outcomes for esophageal cancer, melanoma, and prostate cancer.

Main Methods:

• Analysis of the NCDB 2022 adult participant user file, encompassing 1,331,740 cancer diagnoses from 1,250 Commission on Cancer (CoC) hospitals.
• Examination of the five most common adult cancers by sex.
• Detailed review of treatment and survival data for esophageal cancer, melanoma, and prostate cancer.

Main Results:

• The five most common cancers differed by sex: Prostate, Lung, Melanoma, Urinary Bladder, and Colon in men; Breast, Lung, Corpus Uteri, Colon, and Melanoma in women.
• Approximately half of esophageal cancer patients presented with Stage IV disease, with most not undergoing resection; survival decreased with higher stage and grade.
• Melanoma most frequently presented as Stage I disease; survival was poorer with increased stage and ulceration. Prostate cancer patients were often diagnosed with Stage II disease; survival depended on stage, grade, and PSA levels.

Conclusions:

• Cancer incidence and commonality vary significantly by sex.
• Early detection and treatment stage are critical factors influencing survival outcomes for esophageal cancer, melanoma, and prostate cancer.
• Treatment modalities, including surgical resection and prostatectomy, play a role in patient outcomes, but are often stage-dependent.