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Updated: Jan 22, 2026

In vitro Assessment of Cardiac Reprogramming by Measuring Cardiac Specific Calcium Flux with a GCaMP3 Reporter
Published on: February 22, 2022
Cardiac Fibroblastoma Presenting as NSTEMI
Deeksha Grover1, Anirudh Palicherla2, Hasaan Ahmed2
1Wellstar Spalding Regional Hospital, Griffin, Georgia, USA.
Background:
Myocardial infarction with nonobstructive coronary arteries (MINOCA) represents ∼8% of acute myocardial infarctions, with causes including myocarditis, coronary spasm, and embolization from cardiac tumors.
Case Summary:
A 59-year-old woman presented with exertional chest pain and elevated troponins, consistent with non-ST-segment elevation myocardial infarction. Coronary angiography showed normal coronaries. Cardiac magnetic resonance imaging revealed a small ischemic infarct, prompting review of prior computed tomography, which identified a small aortic valve mass. Transesophageal echocardiography confirmed a mobile lesion. Surgical excision revealed a benign fibroblastoma, an extremely rare cardiac tumor.
Conclusions:
This case highlights the importance of thorough imaging review in MINOCA and expands the spectrum of cardiac tumors implicated in coronary embolization. This is to our knowledge one of the first reports of a cardiac fibroblastoma.
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