Related Experiment Video
Updated: Jan 22, 2026

Formulation of Zinc-Based Nanomaterials using the Eucommia ulmoides Bark Extract and their Wound Healing Potential
Published on: December 27, 2024
Wound healing potential of methanolic extract of Wrightia tinctoria fresh leaf
Subramanian Subalakshmi1, Dhanaventhan Simyaa1, Subramanian Sruthivani1
1Chemical Biology Lab (ASK-II-409), School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, Tamilnadu, India.
Abstract:
Fresh leaves of Wrightia tinctoria plant is used by traditional healers in India for wound healing. Even though few research studies conducted on the wound healing property of dry leaves, no scientific proof available for fresh leaf extract of W. tinctoria. The present work aims to analyse the phytochemical components in the fresh leaves of W. tinctoria and also to investigate the wound healing potential in excision wound model. The methanolic extract of fresh leaves possess high levels of phytochemical compounds and the GC-MS analysis indicated the presence of major phytochemicals 8-prenylnaringenin, bilobalide and trans-cinnamic acid. Methanolic extract recorded superior antioxidant, anti-inflammatory and antibacterial activities than other solvent extracts and also protected from intracellular generation of ROS in PBMC cells. Further, it induced angiogenesis in CAM model and found to be safe based on MTT assay. In vivo studies revealed that ointment prepared from methanolic extract of W. tinctoria fresh leaf healed the wound faster (100%) than betadine-treated on 13th day. Hence, methanolic extract of fresh leaves of W. tinctoria could be explored as potential candidate for the development of green and safe wound healing drug.
Related Concept Videos
Segregation in Fresh Concrete
Bleeding in Fresh Concrete
Bleeding can cause several issues in the concrete structure. Sometimes, the rising water gets trapped beneath large aggregate...
Potential Energy
Chemical bonds that form attractive forces between atoms also contain potential energy, called chemical energy. When a chemical reaction...
Potential Energy
Standard Electrode Potentials
Cell Potential and Free Energy
Thermodynamics is the branch of physics dealing with the relationship between heat and other forms of energy. In an electrochemical cell, chemical energy is converted into electrical energy.
Thus, a link can be predicted between cell potential, free energy change, and the equilibrium constant for the reaction. Cell potential can also be measured as the oxidant or the reducing strength, and similar acid-base strength measures are reflected in equilibrium...

