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Related Experiment Video

Updated: Jan 23, 2026

Data Collection on Marine Litter Ingestion in Sea Turtles and Thresholds for Good Environmental Status

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Published on: May 18, 2019

Reviewing Marine Bioactive Compounds From the Red Sea: Advancing Therapeutic Applications While Navigating

Mohammed F Hawwal¹, Nadeem Sayyed², Omer I Fantoukh¹

¹Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Chemistry & Biodiversity

|January 21, 2026

Summary

Marine organisms from the Red Sea yield novel bioactive compounds with therapeutic potential. Research highlights their antimicrobial, anticancer, and anti-inflammatory properties, yet challenges remain for clinical application.

Keywords:

Red Sea biodiversity bioactive compounds drug discovery marine organisms microalgae therapeutic potential

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Area of Science:

Marine Biology
Pharmacology
Biotechnology

Background:

The Red Sea is a rich source of marine biodiversity.
Marine organisms produce bioactive compounds with therapeutic potential.
A decade of research has focused on isolating and characterizing these compounds.

Purpose of the Study:

To review the isolation, characterization, and biological activities of compounds from Red Sea marine organisms.
To identify challenges and propose future directions for drug discovery from this ecosystem.

Main Methods:

Literature review of research over the past decade.
Analysis of extraction techniques (solvent, supercritical fluid, ultrasound-assisted).
Examination of purification and identification methods (chromatography, bioassay-guided fractionation).

Main Results:

Compounds like alkaloids, glycosides, terpenes, and peptides exhibit antimicrobial, anticancer, anti-inflammatory, and neuroprotective effects.
Various extraction and purification methods have been employed.
Challenges include limited availability, complex extraction, and regulatory hurdles.

Conclusions:

Red Sea marine natural products offer significant therapeutic promise.
Overcoming extraction, characterization, and regulatory challenges is crucial for clinical translation.
Interdisciplinary approaches integrating marine biology with technologies like deep learning are needed for future drug discovery and conservation efforts.