Related Experiment Video
Updated: Jan 23, 2026
09:24
Repeated Measurement of Respiratory Muscle Activity and Ventilation in Mouse Models of Neuromuscular Disease
Published on: April 17, 2017
13.6K
Factor Affecting the Receiving Repeated Ventilation Tube Insertion in Children With Cleft Palate
Thanakit Malaikritsanachalee1, Vannipa Vathanophas1, Sarut Chaisrisawadisuk2
1Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Summary
Children with cleft palate needing repeated ventilation tube insertion (VTI) for otitis media with effusion (OME) often have thick middle ear fluid, eardrum retraction, or hearing loss. A new scoring system helps predict this risk.
Area of Science:
- Otolaryngology
- Pediatric Surgery
- Audiology
Background:
- Otitis media with effusion (OME) is common in children with cleft palate (CP).
- Ventilation tube insertion (VTI) is a standard treatment for OME in this population.
- Identifying factors for repeat VTI is crucial for optimizing management.
Purpose of the Study:
- To identify predictors of repeated ventilation tube insertion (VTI) in children with cleft palate (CP).
- To develop a risk prediction scoring system for repeat VTI in CP patients with otitis media with effusion (OME).
Main Methods:
- Retrospective cohort study of 127 children with CP undergoing VTI and palatoplasty.
- Analysis of ten potential risk factors including middle ear fluid type, tympanic membrane (TM) status, and hearing level.
- Logistic regression used to develop a predictive scoring system.
Main Results:
- Thick middle ear fluid (OR 3.18), TM retraction (OR 4.06), and premyringotomy hearing level >40 dB (OR 3.50) were independent predictors of repeat VTI.
- A scoring system (0-4 points) demonstrated acceptable predictive discrimination (AUC = 0.732).
Conclusions:
- Children with TM retraction, thick middle ear fluid, or significant hearing loss face a higher risk of requiring repeat VTI.
- The developed scoring system aids in early risk identification, counseling, and targeted follow-up for improved middle ear outcomes in CP patients.
Related Concept Videos
01:19Factors Affecting Pulmonary Ventilation
3.0K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
3.0K
01:23Mechanical Ventilation II: Invasive Ventilation
660
Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
660
01:23Mechanical Ventilation III: Noninvasive Ventilation
541
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
Noninvasive Positive-Pressure Ventilation...
541
01:15Receiver Operating Characteristic Plot
479
A ROC (Receiver Operating Characteristic) plot is a graphical tool used to assess the performance of a binary classification model by illustrating the trade-off between sensitivity (true positive rate) and specificity (false positive rate). By plotting sensitivity against 1 - specificity across various threshold settings, the ROC curve shows how well the model distinguishes between classes, with a curve closer to the top-left corner indicating a more accurate model. The area under the ROC curve...
479
01:24Pulmonary Ventilation: Inhalation
7.7K
Pulmonary ventilation is a vital process that ensures the exchange of oxygen and carbon dioxide in the lungs. It refers to the movement of air into and out of the lungs, enabling the body to obtain oxygen and remove waste carbon dioxide. In this article, we will explore the intricacies of pulmonary ventilation, including its underlying principles, mechanisms, and the interplay of pressures within the respiratory system.
Boyle's law becomes particularly pertinent when examining respiratory...
Boyle's law becomes particularly pertinent when examining respiratory...
7.7K
01:16Uterine Tubes
2.1K
The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
2.1K