Related Experiment Video
Updated: Jan 23, 2026
Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
Integrated Assessment of Arterial Stiffness and Right Atrial Function in Type 2 Diabetes With Cardiovascular
Tsuyoshi Tabata1, Kazuhiro Shimizu2, Toshio Kinoshita1,2
1Department of Clinical Functional Physiology, Toho University Sakura Medical Center.
Background:
Cardiovascular autonomic neuropathy (CAN) is a major complication of type 2 diabetes mellitus (T2DM), but the roles of arterial stiffness and right atrial (RA) function in CAN remain unclear.
Methods And Results:
In 120 patients with T2DM, we assessed short-term heart rate variability (CVR-R), cardio-ankle vascular index (CAVI), and two-dimensional speckle-tracking echocardiography (2DSTE). CAN was defined as CVR-R <2%. Multivariable analysis showed that higher CAVI and lower RA function composite scores were independently associated with CAN.
Conclusions:
Both increased arterial stiffness and impaired RA function characterized CAN, indicating a key cardiovascular interaction. Combined CAVI and RA strain assessment may aid early detection.
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