Association of Particulate Matter (PM2.5) With COVID-19 Infection and Mortality in Low-and Middle-income Asian Countries: A Systematic Review and Meta-analysis

  • 0Department of Environmental Health, Faculty of Public Health, Universitas Sriwijaya, Ogan Ilir Regency, Indonesia.

Summary

This summary is machine-generated.

Particulate matter (PM2.5) pollution significantly increases the risk of COVID-19 infection in low- and middle-income Asian countries. Evidence for a link to COVID-19 mortality remains insufficient, highlighting the need for improved air quality policies.

Area Of Science

  • Environmental Health
  • Epidemiology
  • Public Health

Background

  • Low- and middle-income Asian countries face a high burden of particulate matter (PM2.5) pollution.
  • Data on the association between PM2.5 exposure and COVID-19 outcomes in this region are limited.

Purpose Of The Study

  • To quantify the association between PM2.5 exposure and the risks of COVID-19 infection and mortality in low- and middle-income Asian countries.
  • To provide evidence for public health strategies and air quality control policies.

Main Methods

  • Systematic review and meta-analysis of observational studies.
  • Search of PubMed, Scopus, and other databases up to December 31, 2024.
  • Random-effects model used to calculate pooled effect sizes and 95% confidence intervals (CIs).

Main Results

  • Fourteen studies were included, showing a significant positive association between PM2.5 exposure and COVID-19 infection for both short-term (RR, 1.12; 95% CI, 1.07-1.18) and long-term exposure (RR, 1.41; 95% CI, 1.28-1.56).
  • A non-significant positive association was found between short-term PM2.5 exposure and COVID-19 mortality (RR, 1.37; 95% CI, 0.80-2.33).
  • High heterogeneity was observed, but findings for infection remained robust.

Conclusions

  • PM2.5 exposure is a significant risk factor for COVID-19 infection in low- and middle-income Asian countries.
  • Current evidence is insufficient to link PM2.5 exposure to COVID-19 mortality.
  • Strengthened air quality control policies are crucial for mitigating respiratory pandemic impacts.

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