Related Experiment Video
Updated: Jan 23, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Giant Cell Arteritis Mimicking Temporomandibular Disorder: Diagnostic Value of Temporal Artery Halo Sign
Jumi Nakata1,2, Fu Sakai1, Kana Ozasa1
1DDS, Department of general internal medicine Musashino Tokushukai Hospital, Tokyo, Japan.
Abstract:
Giant-cell arteritis (GCA) involving the temporal arteries primarily affects the older adults, with symptoms that include head pain and tenderness. GCA may mimic temporomandibular disorders by causing jaw opening difficulty. Herein, we report an 89-year-old man who presented with jaw fatigue during meals, frontal headache, and low-grade fever. Examination revealed tenderness and dilatation of the right superficial temporal artery, jaw claudication, an elevated C-reactive protein (8.62 mg/dL), and erythrocyte sedimentation rate of 97 mm/h. Magnetic resonance imaging of the brain showed a small acute infarct. Autoimmune serology and blood culture results were negative. Temporal artery ultrasonography demonstrated a halo sign, and the patient met four of the five American College of Rheumatology criteria, confirming GCA. Treatment with prednisolone (0.5 mg/kg) rapidly improved symptoms and laboratory findings; however, sudden bilateral visual loss occurred despite steroid pulse therapy, and vision did not recover. The findings of this case highlight that, in older adult patients, the halo sign may serve as a practical alternative to temporal artery biopsy for establishing GCA diagnosis.
Related Concept Videos
Halo Effect
Assessing Body Temperature - Temporal Artery
Step 1: Perform hand hygiene and don a fresh pair of gloves to prevent cross-infection and ensure patient safety.
Step 2: Explain the procedure to the patient to establish trust. Clear communication establishes trust with the patient, ensures they understand what to expect, promotes cooperation, and enhances comfort during the procedure.
Step 3: Assess the patient's...
Diagnostic and Statistical Manual of Mental Disorders (DSM)
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Signs of Puberty
Introduction to the Sign Test

