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Idiopathic Adolescent Miserable Malalignment.

Chloe Farnham1, Marco Gupton2, Melissa Allen2

  • 1Medical College of Georgia at Augusta University, Augusta, GA, USA.

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|January 22, 2026
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Summary
This summary is machine-generated.

Miserable malalignment syndrome (MMS), a hip and knee issue in adolescents, causes pain and dysfunction. Early recognition and management are crucial for preventing long-term joint problems.

Keywords:
Lower extremity orthopaedic surgeryPediatric orthopaedicsRotational osteotomy

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Area of Science:

  • Orthopedics
  • Pediatric Orthopedics
  • Biomechanical Engineering

Background:

  • Miserable malalignment syndrome (MMS) involves increased femoral anteversion and external tibial torsion.
  • Often overlooked in adolescents, idiopathic MMS can cause significant pain, gait abnormalities, and patellofemoral instability.
  • This condition may predispose individuals to premature degenerative joint disease.

Purpose of the Study:

  • To emphasize the clinical relevance of idiopathic adolescent MMS.
  • To provide a framework for assessing and managing this condition.
  • To guide future research directions for adolescent lower limb malalignment.

Main Methods:

  • Review of existing literature on adolescent lower limb torsional deformities.
  • Clinical assessment guidelines including physical examination and gait analysis.
  • Discussion of advanced imaging modalities like CT, MRI, and low-dose radiography for diagnosis.

Main Results:

  • Idiopathic adolescent MMS is a significant cause of hip and knee pain, and functional deficits.
  • Accurate diagnosis requires a combination of clinical evaluation and advanced imaging.
  • Surgical correction (derotational osteotomy) shows promise for improving pain and function.

Conclusions:

  • Adolescent MMS is a clinically significant condition, not merely a benign finding.
  • Early diagnosis and appropriate management are essential to improve patient outcomes.
  • Further research is needed to establish standardized treatment protocols and long-term data.