Related Experiment Video For adenoid basal carcinoma
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Adenoid basal carcinoma of the uterine cervix: a case report
1Department of Pathology, Tongde Hospital of Zhejiang Province, Hangzhou, China.
Background:
Adenoid basal carcinoma (ABC) is a rare human papillomavirus (HPV)-related malignancy of the uterine cervix that predominantly affects postmenopausal women, and it is a low-grade tumor with a favorable prognosis. This report presents a case of ABC along with a detailed immunohistochemical analysis.
Case Presentation:
A 65-year-old woman tested positive for HPV types 16, 35, and 56 during routine screening. A subsequent cervical biopsy indicated adenocarcinoma. The patient was asymptomatic. She underwent radical hysterectomy, bilateral salpingo-oophorectomy, and bilateral pelvic lymph node dissection. A comprehensive pathological examination of the hysterectomy specimen confirmed ABC with a focal component of high-grade squamous intraepithelial lesion (HSIL). The postoperative course was uneventful, and no recurrence or metastasis was observed during 4 years of follow-up.
Conclusion:
Adequate tissue sampling and appropriate immunohistochemical profiling are valuable for accurate diagnosis and differentiation of ABC from other malignant cervical lesions.
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