Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Surface Appendages of Archaea01:23

Surface Appendages of Archaea

617
Archaeal surface appendages are highly specialized structures essential for environmental adaptation, encompassing roles in adhesion, biofilm formation, and motility. Among these appendages, pili and archaella stand out for their distinct morphologies and functionalities, enabling archaea to thrive in diverse and often extreme environments.Pili: Adhesion and Biofilm FormationPili are filamentous structures assembled from pilin protein subunits, primarily contributing to adhesion and biofilm...
617
Sex-linked Disorders01:43

Sex-linked Disorders

108.5K
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
108.5K
Difference from Background: Limit of Detection01:05

Difference from Background: Limit of Detection

8.1K
The limit of detection (LOD) is the smallest amount of analyte that can be distinguished from the background noise. The LOD value corresponds to the concentration at which the analyte signal is three times larger than the standard deviation of the blank signal. Below this value, the analyte signal cannot be differentiated from the background noise. It is calculated by dividing the calibration slope by 3 times the standard deviation of the blank signals.
The LOD indicates the presence or absence...
8.1K
Electric Potential and Potential Difference01:16

Electric Potential and Potential Difference

5.6K
Suppose a positive test charge moves away from a positive static charge, then the Coulomb force does positive work, and its electric potential energy decreases. The potential energy per unit charge is defined as the electric potential. The electric potential is independent of the test charge.
When a test charge moves from the initial to the final position, the electric potential difference between those positions is defined as the ratio of the change in the potential energy to the charge on the...
5.6K
Identifying Statistically Significant Differences: The F-Test01:14

Identifying Statistically Significant Differences: The F-Test

3.2K
The F-test is used to compare two sample variances to each other or compare the sample variance to the population variance. It is used to decide whether an indeterminate error can explain the difference in their values. The underlying assumptions that allow the use of the F-test include the data set or sets are normally distributed, and the data sets are independent of each other. The test statistic F is calculated by dividing one variance by another. In other words, the square of one standard...
3.2K
Sum and Difference OpAmps01:22

Sum and Difference OpAmps

1.3K
Operational amplifiers (op-amps) are versatile devices that extend beyond amplification. In this context, two specific op-amp configurations are explored: the summing and difference amplifiers.
A summing amplifier, or an adder, utilizes an op-amp to merge multiple input signals into a single output signal. When audio signals are introduced into its input channels, the input resistors initiate currents that traverse feedback resistors, resulting in an output voltage. Applying Kirchhoff's current...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

COVID-19 Vaccine Reactogenicity Marks an Innate Inflammatory Response Associated With HLA Variation and Enhanced Protection.

Research square·2026
Same author

Exploring Phosphatidylethanol Cutoffs for Self-Reported Unhealthy Alcohol Use: An International Multi-Site Analysis.

Alcohol, clinical & experimental research·2026
Same author

Leveraging Self-Reporting in an Existing e-Cohort to Identify Clinically Relevant Mitral Valve Prolapse: Pilot Questionnaire Study.

JMIR formative research·2026
Same author

Digital Health Intervention to Promote Lifelong Specialized Care in Adults With Congenital Heart Disease: Theory-Driven Community Co-Designed Study.

Journal of medical Internet research·2026
Same author

Multileaflet BASILICA to Prevent Coronary Obstruction in a Small Aortic Annulus.

JACC. Cardiovascular interventions·2026
Same author

Rare coding variant architecture and gene discovery from 130,000 sequenced cases of atrial fibrillation.

Research square·2026
Same journal

Proteomics-Based Soluble Urokinase Plasminogen Activator Receptor Levels Are Associated With Adverse Cardiovascular Outcomes in the General Population: Insights From the UK Biobank.

Journal of the American Heart Association·2026
Same journal

Sex-Specific Association Between Socioeconomic Status and Stroke Mortality.

Journal of the American Heart Association·2026
Same journal

Social Determinants of Health and Cardiovascular Disease-Related Outcome Disparities Among Breast Cancer Survivors: A Systematic Review.

Journal of the American Heart Association·2026
Same journal

Graded Associations Between Left Ventricular Ejection Fraction Improvement and Cardiorenal Outcomes in Heart Failure With Improved Ejection Fraction.

Journal of the American Heart Association·2026
Same journal

Early Multimodal Motor Training After Stroke Promotes Motor Recovery and Whole-Brain Structural Remodeling.

Journal of the American Heart Association·2026
Same journal

EAT-Lancet Diet, Plasma Metabolites, and Risk of Peripheral Artery Disease: A Prospective Cohort Study.

Journal of the American Heart Association·2026
See all related articles

Related Experiment Video

Updated: Jan 23, 2026

Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems
08:49

Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems

Published on: August 2, 2024

1.3K

Sex and Racial Differences in Left Atrial Appendage Morphology.

Ahmed Wahaj1, Madeline E Mauri2, Matthew J Bocchese2

  • 1Rawalpindi Medical University Rawalpindi Pakistan.

Journal of the American Heart Association
|January 22, 2026
PubMed
Summary
This summary is machine-generated.

Black patients with atrial fibrillation have a higher prevalence of the cauliflower left atrial appendage morphology, a high-stroke risk factor. This finding suggests potential racial disparities in stroke risk associated with LAA anatomy.

Keywords:
atrial fibrillationcerebrovascular accidentleft atrial appendagerace

More Related Videos

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
07:28

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Published on: October 11, 2024

717
Sex Differences in Mouse Hippocampal Astrocytes after In-Vitro Ischemia
08:32

Sex Differences in Mouse Hippocampal Astrocytes after In-Vitro Ischemia

Published on: October 25, 2016

13.9K

Related Experiment Videos

Last Updated: Jan 23, 2026

Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems
08:49

Author Spotlight: Enhancing Graft Viability Assessment Through Quantitative Metrics and Innovative Reservoir Systems

Published on: August 2, 2024

1.3K
Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation
07:28

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Published on: October 11, 2024

717
Sex Differences in Mouse Hippocampal Astrocytes after In-Vitro Ischemia
08:32

Sex Differences in Mouse Hippocampal Astrocytes after In-Vitro Ischemia

Published on: October 25, 2016

13.9K

Area of Science:

  • Cardiology
  • Radiology
  • Medical Imaging

Background:

  • Atrial fibrillation (AF) patients who are Black or female experience higher stroke rates.
  • Specific left atrial appendage (LAA) morphologies are linked to increased stroke risk.
  • Racial and sexual variations in LAA anatomy and their association with stroke risk are largely unexplored.

Purpose of the Study:

  • To investigate potential associations between patient race and sex with LAA morphology.
  • To explore if LAA anatomical differences contribute to stroke risk disparities in Black and female AF patients.

Main Methods:

  • Computed tomography (CT) scans of 211 patients were analyzed for LAA morphology.
  • LAA morphologies were categorized using a scoring system based on thrombus risk (chicken wing, windsock, cactus, cauliflower).
  • Statistical analyses, including Wilcoxon rank-sum and Fisher's exact tests, were used to compare morphology prevalence and scores across racial and sex groups. Logistic regression identified associations between race/sex and high-risk LAA morphologies.

Main Results:

  • No significant differences in projected stroke risk scores were observed between Black and non-Black patients, or between men and women.
  • The 'cauliflower' LAA morphology, associated with the highest stroke risk, was significantly more prevalent in Black patients compared to non-Black patients (adjusted OR, 4.8; P=0.035).
  • While 'cauliflower' morphology was more frequent in women, this finding did not reach statistical significance (P=0.063).

Conclusions:

  • The 'cauliflower' LAA morphology, a high-risk factor for stroke, shows a higher prevalence in Black patients.
  • The observed difference in LAA morphology between sexes did not achieve statistical significance.
  • These preliminary findings suggest potential racial disparities in stroke risk due to LAA anatomy, warranting further investigation despite the study's limitations in statistical power.