Larger-volume Silicone Breast Implants Are Safe in Breast Reconstruction: the Athena Multicenter, Prospective Study of 400 Patients
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View abstract on PubMed
Summary
This summary is machine-generated.Larger silicone breast implants (≥930cc) are safe and effective for postmastectomy reconstruction. Patients experienced improved satisfaction and well-being, with no increased complications related to larger volumes.
Area Of Science
- Plastic Surgery
- Reconstructive Surgery
- Biomaterials Science
Background
- The maximum available silicone breast implant volume for reconstruction in the US was 800cc.
- This study investigated the safety of larger MENTOR® MemoryGel® Ultra-High Profile implants (≥930cc).
Purpose Of The Study
- To evaluate the safety and effectiveness of larger-volume silicone breast implants in women undergoing postmastectomy reconstruction.
- To assess patient-reported outcomes and surgical complications associated with these implants.
Main Methods
- A 10-year, multicenter, open-label, prospective study.
- Kaplan-Meier curves and Cox regression analyzed surgical outcomes.
- Breast-Q surveys assessed patient-reported effectiveness at 3 years.
Main Results
- Four hundred women (225 primary, 175 revision) were enrolled, with a mean BMI of 35.8 kg/m2.
- At 3 years, cumulative complication incidence was 63.0%, reoperation rate was 24.5%, and explantation rate was 15.8%.
- No significant association between complications and implant volume (≥1135cc vs. <1135cc) was found. Radiation and smoking history predicted complications.
- Breast-Q scores showed significant improvements in satisfaction, psychosocial, sexual, and physical well-being (P<0.0001).
Conclusions
- Larger-volume silicone breast implants (≥930cc) are a safe and effective option for postmastectomy reconstruction.
- These implants significantly improve patient satisfaction and overall well-being.
- The study provides crucial data for reconstructive surgeons and patients considering larger implant volumes.
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