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Updated: Jan 24, 2026

Cellular Affinity of Particle-Stabilized Emulsion to Boost Antigen Internalization
Published on: September 2, 2022
Stabilization of high internal phase Pickering emulsions using sunflower lecithin-protein complexes: Characterization
Can Wang1, Lei Hao2, Yaping Bao1
1Engineering Research Center of Bio-process, Ministry of Education, Key Laboratory for Agricultural Products Modern Processing of Anhui Province, School of Food and Biological Engineering, Hefei University of Technology, Hefei, 230009, China.
Abstract:
Food-grade Pickering high internal phase emulsions (HIPEs) stabilized by composite particles have gained significant attention. This study employed two sunflower lecithins (SL50 and SL90) with distinct phosphatidylcholine contents, combined with whey protein isolate (WPI) and sodium caseinate (SC), to synthesize composite particles for stabilizing oil-in-water HIPEs. Characterized by particle size, zeta potential, FTIR, TGA, TEM, and interfacial tension tests, the composite particles-SL50-WP-SC and SL90-WP-SC-formed HIPEs with stable oil phase contents up to 85% and 83%, respectively, via electrostatic, hydrophobic, and hydrogen bonding interactions. The HIPEs exhibited excellent stability under thermal, storage, ionic conditions, and at pH 6-11. When applied for β-carotene encapsulation, they significantly enhanced its retention in various environments. In vitro digestion tests showed improved β-carotene bioaccessibility and free fatty acid release, facilitating gastrointestinal delivery. These HIPEs represent promising delivery systems for bioactive compounds, enriching theoretical insights into food-grade composite-stabilized Pickering emulsions and guiding functional food development.
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