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Updated: Jan 24, 2026

Cellular Affinity of Particle-Stabilized Emulsion to Boost Antigen Internalization
Published on: September 2, 2022
Oat protein isolate-shellac nanoparticle stabilized Pickering emulsions with elastic interfacial layer: From
Chen Yang1, Zitan Liu2, Zikuan Guan2
1College of Food Science and Engineering, Tianjin University of Science & Technology, Tianjin, 300457, China; Youzifu (Tianjin) Food Technology Co., LTD, China; Weihai Biohigh Biotechnology Co., LTD, China.
None:
This study systematically investigated the interfacial mechanism of oat protein isolate -shellac (OPI/S) nanoparticles at the oil-water (O/W) interface under neutral condition, and explored the promising performance of OPI/S stabilized Pickering emulsions as an efficient delivery system for lipid-soluble nutrients. The results demonstrated that OPI/S2:1 nanoparticles synergistically stabilized Pickering emulsion by constructing a dense elastic interfacial film on oil droplets through exposed hydrophobic sites, while forming a compact 3D network in the continuous phase via interparticle hydrophobic interactions. Such dense film and favorable interactions significantly enhanced protein adsorption rate and elevated interfacial protein concentration compared to OPI nanoparticles alone. Such elastic interfacial film of OPI/S2:1-stabilized Pickering emulsion exhibited superior encapsulation and protection ability for curcumin, where the encapsulation efficiency, retention rate and bioaccessibility increased significantly by 19.4%, 37.8%, and 40.6%, respectively, after UV radiation and heat treatment, while demonstrated excellent controlled release properties in simulated gastrointestinal tract, establishing exceptional delivery systems for lipophilic nutrients.
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