Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bioequivalence Data: Statistical Interpretation01:16

Bioequivalence Data: Statistical Interpretation

201
Body:The statistical interpretation of bioequivalence data is a significant aspect of pharmaceutical research. Bioequivalence refers to the absence of any significant difference in the rate and extent to which the active ingredient in pharmaceutical products becomes available at the site of drug action when administered at the same molar dose under similar conditions. This helps determine if different drug products have similar absorption rates, ensuring their interchangeability.Statistical...
201
Relative Strengths of Conjugate Acid-Base Pairs02:29

Relative Strengths of Conjugate Acid-Base Pairs

51.6K
Brønsted-Lowry acid-base chemistry is the transfer of protons; thus, logic suggests a relation between the relative strengths of conjugate acid-base pairs. The strength of an acid or base is quantified in its ionization constant, Ka or Kb, which represents the extent of the acid or base ionization reaction. For the conjugate acid-base pair HA / A−, the ionization equilibrium equations and ionization constant expressions are
51.6K
Acid and Bases: Ka, pKa, and Relative Strengths02:35

Acid and Bases: Ka, pKa, and Relative Strengths

32.9K
This lesson delves into a critical aspect of the relative strengths of acids and bases. The strength of an acid is evaluated by the acid dissociation into its conjugate base and a hydronium ion in water. The complete dissociation of a strong acid is confirmed with a very high concentration of hydronium ions. As a result, an incomplete dissociation process affirms a weak acid. Therefore, the equilibrium is in the forward direction for strong acids and backward for weak acids in these reactions.
32.9K
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models01:06

Model Approaches for Pharmacokinetic Data: Distributed Parameter Models

244
Pharmacokinetic models are mathematical constructs that represent and predict the time course of drug concentrations in the body, providing meaningful pharmacokinetic parameters. These models are categorized into compartment, physiological, and distributed parameter models.
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
244
Acid/Base Strengths and Dissociation Constants03:02

Acid/Base Strengths and Dissociation Constants

69.3K
The relative strength of an acid or base is the extent to which it ionizes when dissolved in water. If the ionization reaction is essentially complete, the acid or base is termed strong; if relatively little ionization occurs, the acid or base is weak. There are many more weak acids and bases than strong ones. The most common strong acids and bases are listed below:
69.3K
Empirical Method to Interpret Standard Deviation01:09

Empirical Method to Interpret Standard Deviation

9.4K
The empirical rule, also known as the three-sigma rule, allows a statistician to interpret the standard deviation in a normally distributed dataset. The rule states that 68% of the data lies within one standard deviation from the mean, 95% lies within two standard deviations from the mean, and 99.7% lies within three standard deviations from the mean. Additionally, this rule is also called the 68-95-99.7 rule.
This rule is used widely in statistics to calculate the proportion of data values...
9.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[ATM/H2AX and repair of sperm-DNA damage during cryopreservation].

Zhonghua nan ke xue = National journal of andrology·2011
Same author

Predicting accident frequency at their severity levels and its application in site ranking using a two-stage mixed multivariate model.

Accident; analysis and prevention·2011
Same author

Photothermally enhanced photodynamic therapy delivered by nano-graphene oxide.

ACS nano·2011
Same author

[Characteristics of soil respiration in Phyllostachys edulis forest in Wanmulin Natural Reserve and related affecting factors].

Ying yong sheng tai xue bao = The journal of applied ecology·2011
Same author

Quality changes in sea urchin (Strongylocentrotus nudus) during storage in artificial seawater saturated with oxygen, nitrogen and air.

Journal of the science of food and agriculture·2011
Same author

Global effect of an RNA polymerase β-subunit mutation on gene expression in the radiation-resistant bacterium Deinococcus radiodurans.

Science China. Life sciences·2011
Same journal

Peripheral B-cell receptor repertoire predicts immune-related adverse events following immune checkpoint inhibitor therapy in advanced renal cell carcinoma.

Scientific reports·2026
Same journal

Effects of black soldier fly (Hermetia illucens L.) larvae zoocompost on the mineral element content of blue honeysuckle berries.

Scientific reports·2026
Same journal

Investigation on absorption refrigeration performance of R1243zf with imidazolium ionic liquid as the working pairs.

Scientific reports·2026
Same journal

DeepTriage-CN: integrating clinical text with vital signs for emergency department admission prediction in an aging population.

Scientific reports·2026
Same journal

Gold nanoparticles as dual-action antiviral agents: disruption of SARS-CoV-2 viral envelopes and RNA integrity.

Scientific reports·2026
Same journal

Comparison of capillary microsampling and venous blood for multi-pathogen serosurveillance.

Scientific reports·2026
See all related articles

Related Experiment Video

Updated: Jan 24, 2026

Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis
07:11

Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis

Published on: November 10, 2023

3.3K

Prediction method for rock shear strength parameters based on data-driven and interpretability analysis.

Zi-Jun Jin1, Chao Wang2,3,4, Shuai Qi1

  • 1Faculty of Land Resources Engineering, Kunming University of Science and Technology, Kunming, 650093, China.

Scientific Reports
|January 22, 2026
PubMed
Summary
This summary is machine-generated.

This study introduces a new Chaos-Improved Sparrow Search Algorithm-Stacking (CISSA-Stacking) model for accurately predicting rock shear strength parameters. The CISSA-Stacking model significantly outperforms traditional methods, offering a practical tool for engineers.

Keywords:
Chaos-improved sparrow search algorithmIntelligent predictionRock shear strength parametersSHAP interpretability analysisStacking ensemble algorithm

More Related Videos

Prediction of HIV-1 Coreceptor Usage Tropism by Sequence Analysis using a Genotypic Approach
07:06

Prediction of HIV-1 Coreceptor Usage Tropism by Sequence Analysis using a Genotypic Approach

Published on: December 1, 2011

13.7K
A Data-Driven Approach to Quantifying Immune States in Sepsis
07:42

A Data-Driven Approach to Quantifying Immune States in Sepsis

Published on: February 7, 2025

486

Related Experiment Videos

Last Updated: Jan 24, 2026

Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis
07:11

Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis

Published on: November 10, 2023

3.3K
Prediction of HIV-1 Coreceptor Usage Tropism by Sequence Analysis using a Genotypic Approach
07:06

Prediction of HIV-1 Coreceptor Usage Tropism by Sequence Analysis using a Genotypic Approach

Published on: December 1, 2011

13.7K
A Data-Driven Approach to Quantifying Immune States in Sepsis
07:42

A Data-Driven Approach to Quantifying Immune States in Sepsis

Published on: February 7, 2025

486

Area of Science:

  • Geotechnical Engineering
  • Computational Intelligence
  • Machine Learning

Background:

  • Predicting rock shear strength is crucial for geotechnical engineering safety.
  • Existing models face limitations in handling complex nonlinearities and hyperparameter optimization.
  • Accurate estimation of rock shear strength parameters (cohesion 'c' and friction angle 'φ') is essential for infrastructure design and stability analysis.

Purpose of the Study:

  • To develop a novel, robust framework for predicting rock shear strength parameters.
  • To address the challenge of random hyperparameter selection in ensemble models.
  • To enhance prediction accuracy and interpretability in geotechnical engineering applications.

Main Methods:

  • A stacking ensemble model was constructed using LightGBM, XGBoost, CatBoost, and Random Forest as base learners, with XGBoost as the meta-learner.
  • The Chaos-Improved Sparrow Search Algorithm (CISSA), incorporating tent chaotic mapping and hybrid mutation, was developed to optimize the stacking model's hyperparameters.
  • The model was trained and validated on 199 rock datasets using fivefold cross-validation, with performance evaluated using R², RMSE, and MAE. SHAP analysis was used for interpretability.

Main Results:

  • The CISSA-Stacking model achieved high accuracy, with R² values of 0.9936 for cohesion (c) and 0.9744 for friction angle (φ).
  • Performance metrics (RMSE, MAE) demonstrated the model's superior accuracy over benchmark methods.
  • SHAP analysis identified key predictive factors: Vp, UCS, BTS, and ρ for cohesion, and ρ, UCS, Vp, and BTS for friction angle.

Conclusions:

  • The developed CISSA-Stacking model offers a significant advancement in predicting rock shear strength parameters.
  • The optimized ensemble approach provides superior accuracy and reliability compared to conventional methods.
  • An intelligent prediction software was created, enabling rapid and accurate estimation of rock shear strength parameters for practical engineering applications.