Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Veins of Upper Limbs01:17

Veins of Upper Limbs

4.0K
The human circulatory system, a marvel of biological engineering, is a complex network of vessels that transport blood throughout the body. Among these, the veins responsible for carrying blood from the upper limbs are divided into two categories: deep and superficial.
The deep venous system is primarily composed of the ulnar and radial veins. The ulnar vein, which drains the fingers through the superficial palmar venous arches, and the radial vein, which serves the palms via the deep palmar...
4.0K
Arteries of the Upper Limbs01:12

Arteries of the Upper Limbs

2.2K
The subclavian artery transitions into the axillary artery as it exits the chest and enters the axillary region. This artery is critical for supplying blood to the shoulder area, including the head of the humerus, through the humeral circumflex arteries. As the vessel continues into the upper arm or brachium, it becomes the brachial artery. This artery plays a key role in vascularizing the brachial region and bifurcates at the elbow into several branches. These branches include the deep...
2.2K
Bones of the Upper Limb: Ulna01:15

Bones of the Upper Limb: Ulna

4.3K
The ulna and radius are parallel bones of the antebrachium or the forearm. The ulna lies medially and consists of a bony tip called the olecranon process at its proximal end. This hook-like projection articulates with the olecranon fossa of the humerus and forms the "hinged" ulnohumeral part of the elbow joint. This joint facilitates forearm extension and flexion while preventing its hyperextension. Similarly, the coronoid process, another bony projection on the proximal/anterior side...
4.3K
Bones of the Upper Limb: Radius01:09

Bones of the Upper Limb: Radius

4.6K
The radius is longer of the two bones that make up the human antebrachium or forearm. At the proximal end, the radius articulates with the capitulum of the humerus and the radial notch of the ulna to form the elbow joint. At the distal end, the radius articulates with the ulna via the ulnar notch, forming the distal radioulnar joint. Distally, the radius also attaches to the carpal wrist bones (scaphoid and lunate) to form the radiocarpal joint.
The radius has a nail-shaped head, and a...
4.6K
Bones of the Upper Limb: Humerus01:19

Bones of the Upper Limb: Humerus

7.0K
The upper limb consists of the arm, forearm, wrist, and hand bones. The humerus is the single bone of the upper arm region. Proximally, it has a large, spherical, smooth head that articulates with the glenoid cavity of the scapula to form the glenohumeral or shoulder joint. The margin of the head is the anatomical neck, a residual epiphyseal plate. Laterally it extends to form bony projections called the greater tubercle and the lesser tubercle. Next to the tubercles is the surgical neck, a...
7.0K
Exercise Stress Test01:26

Exercise Stress Test

1.2K
Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ecological assessment of transdiagnostic clinical symptoms in serious mental illness with daily smartphone surveys.

Translational psychiatry·2026
Same author

At-Home Versus in-Clinic Vital Capacity Measurement: Insights From the HEALEY ALS Platform Trial.

Muscle & nerve·2026
Same author

Optimizing Research Operations and Resource Utilization in ALS Care: Insights From the Tofersen Antisense Oligonucleotide Expanded Access Protocol.

Muscle & nerve·2026
Same author

Change in walking cadence as a digital outcome measure of clinically meaningful improvement in gait speed and 6-minute walk test distance after a mobility intervention in older adults.

PloS one·2026
Same author

Functional Activity of TDP-43: A Direct Biomarker for ALS.

medRxiv : the preprint server for health sciences·2026
Same author

Using smartphone surveys to predict next-week suicide attempts.

Journal of psychopathology and clinical science·2026

Related Experiment Video

Updated: Jan 24, 2026

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
07:10

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Published on: August 24, 2019

10.3K

Short prescribed exercises can quantify upper limb functioning in neurodegenerative disease.

Marcin Straczkiewicz1, Katherine M Burke2,3, Narghes Calcagno4

  • 1Department of Measurement and Electronics, AGH University of Krakow, Krakow, Poland. mstr@agh.edu.pl.

Journal of Neuroengineering and Rehabilitation
|January 22, 2026
PubMed
Summary

Digital health technologies offer new ways to track patient movement. A new method using prescribed exercises effectively quantifies upper limb function in individuals with ALS, reducing the need for prolonged sensor wear.

Keywords:
AlgorithmAmyotrophic lateral sclerosisDigital healthMotor functionUpper extremityWearable accelerometerWrist-worn

More Related Videos

Author Spotlight: Advancing Upper Limb Rehabilitation in Patients with Right Hemisphere Damage Using Assisted Active Exercise
04:43

Author Spotlight: Advancing Upper Limb Rehabilitation in Patients with Right Hemisphere Damage Using Assisted Active Exercise

Published on: February 9, 2024

1.5K
Author Spotlight: Enhancing Post-Stroke Upper Limb Rehabilitation with Robotic Technologies for Improved Motor Recovery and Functional Outcomes
04:49

Author Spotlight: Enhancing Post-Stroke Upper Limb Rehabilitation with Robotic Technologies for Improved Motor Recovery and Functional Outcomes

Published on: September 6, 2024

1.4K

Related Experiment Videos

Last Updated: Jan 24, 2026

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease
07:10

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Published on: August 24, 2019

10.3K
Author Spotlight: Advancing Upper Limb Rehabilitation in Patients with Right Hemisphere Damage Using Assisted Active Exercise
04:43

Author Spotlight: Advancing Upper Limb Rehabilitation in Patients with Right Hemisphere Damage Using Assisted Active Exercise

Published on: February 9, 2024

1.5K
Author Spotlight: Enhancing Post-Stroke Upper Limb Rehabilitation with Robotic Technologies for Improved Motor Recovery and Functional Outcomes
04:49

Author Spotlight: Enhancing Post-Stroke Upper Limb Rehabilitation with Robotic Technologies for Improved Motor Recovery and Functional Outcomes

Published on: September 6, 2024

1.4K

Area of Science:

  • Neurology
  • Biomedical Engineering
  • Digital Health

Background:

  • Digital health technologies (DHTs) can monitor daily movements but require high participant adherence for prolonged use.
  • Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease affecting motor function.

Purpose of the Study:

  • To develop and validate an automated signal processing method for quantifying exercise performance using accelerometry data.
  • To assess the association between exercise metrics and disease progression (ALSFRS-R) in individuals with ALS.
  • To compare the efficacy of prescribed exercise monitoring with traditional free-living metrics.

Main Methods:

  • Analyzed accelerometry data from wrist-worn devices during prescribed exercises in 329 individuals with ALS.
  • Developed an automated method to estimate exercise count, duration, intensity, and similarity.
  • Used linear mixed-effect models to examine associations with time and ALSFRS-R, comparing results with free-living metrics.

Main Results:

  • Exercise duration increased, while intensity and similarity decreased over time, correlating with ALS progression (p < 0.001).
  • Exercise intensity was a robust predictor of upper limb function changes, comparable to free-living metrics (R-squared 0.899 vs. 0.860).
  • As few as five exercise repetitions were sufficient for statistically significant associations with ALSFRS-R.

Conclusions:

  • Prescribed exercise monitoring effectively quantifies upper limb function and tracks ALS decline, comparable to free-living methods.
  • The proposed method reduces participant burden and increases study adherence.
  • This approach enhances diagnostic accessibility and offers an alternative to prolonged sensor wear.