Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Components of Stress01:23

Components of Stress

510
Stress analysis under multiple loading conditions is intricate, necessitating a comprehensive grasp of normal and shearing stresses. Consider a small cube at point O, subjected to stress on all six faces, visible or not. Normal stress components σx, σy, σz act perpendicularly to the x, y, and z axes. Shearing stress components τxy and τxz are exerted on faces perpendicular to these axes.
Interestingly, the hidden cube faces also experience these stresses, equal and...
510
Components of Language01:24

Components of Language

796
Language, whether spoken, signed, or written, consists of specific components: lexicon and grammar. The lexicon is the vocabulary of a language, comprising its words. Grammar is the set of rules used to convey meaning through the lexicon. For example, English grammar adds “-ed” to most verbs to indicate past tense. Words are formed by combining phonemes, which are the basic sound units of a language. Different languages have different sets of phonemes (e.g., “ah” vs.
796
Structure of Lipids03:38

Structure of Lipids

98.5K
Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic...
98.5K
Additional Subnuclear Structures02:10

Additional Subnuclear Structures

5.3K
The eukaryotic nucleus is a double membrane-bound organelle that contains nearly all of the cell’s genetic material in the form of chromosomes. It is rightly called the “brain” of the cell as it shoulders the responsibility of responding to various physiological processes, stress, altered metabolic conditions, and other cellular signals. 
The nucleus contains many membrane-less subnuclear organelles or nuclear bodies, such as nucleoli, Cajal bodies, speckles,...
5.3K
Curvilinear Motion: Rectangular Components01:23

Curvilinear Motion: Rectangular Components

1.2K
Curvilinear motion characterizes the movement of a particle or object along a curved path, notably evident when envisioning a car navigating a winding road. If the car starts at point A, its position vector is established within a fixed frame of reference, where the ratio of the position vector to its magnitude signifies the unit vector pointing in the position vector's direction.
As the car advances, its position evolves over time. Quantifying the car's velocity involves computing the...
1.2K
Drug Binding to Blood Components01:30

Drug Binding to Blood Components

512
When drugs enter systemic circulation, they interact with various components of the blood, including proteins such as human serum albumin (HSA), α1-acid glycoprotein (AAG), lipoproteins, globulins, and red blood cells (RBCs).
HSA is the most abundant plasma protein and is vital in drug binding. It contains distinct drug-binding sites, with different drugs exhibiting affinity for specific sites. There are three main drug-binding domains for HSA: sites I, II, and III. These domains are...
512

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Broad-Spectrum Vaccines: Challenges and Opportunities (A Systematic Review).

Current molecular medicine·2026
Same author

Targeting Drug Metabolism for Triple Negative Breast Cancer: A Systematic Review.

Current cancer drug targets·2026
Same author

The Mutational Landscape of Angiosarcoma: Challenges and Opportunities to Design Management Strategies.

Current molecular medicine·2026
Same author

Integrating microbial bioremediation, multi-omics, and emerging technologies for polycyclic aromatic hydrocarbon (PAHs) detoxification.

Journal of microbiological methods·2026
Same author

Heavy Metals and One Health: Current Status and Future Prospects.

Current medicinal chemistry·2026
Same author

The Role of Mitochondrial Ion Channels in the Evolution of Anticancer Drug Resistance.

Current protein & peptide science·2026

Related Experiment Video

Updated: Jan 24, 2026

In Vitro Assay to Measure Phosphatidylethanolamine Methyltransferase Activity
09:33

In Vitro Assay to Measure Phosphatidylethanolamine Methyltransferase Activity

Published on: January 5, 2016

10.2K

Phosphatidylethanolamine: Structural Component and Beyond.

Swaroop Kumar Pandey1, Ayush Kulshreshtha1, Anuja Mishra1

  • 1Department of Biotechnology, Institute of Applied Science & Humanities, GLA University, Mathura, 281406, U.P., India.

Current Molecular Medicine
|January 23, 2026
PubMed
Summary
This summary is machine-generated.

Phosphatidylethanolamine (PE), vital for cell membranes, is increasingly linked to diseases like NAFLD and cancer. Understanding PE metabolism is key to identifying new disease biomarkers and therapeutic targets.

Keywords:
Alzheimer's diseaseNAFLDParkinson’s diseasePhospholipidbiosynthesiscancer.phosphatidylethanolamine

More Related Videos

Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications
14:43

Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications

Published on: September 23, 2013

11.2K
Concurrent Quantification of Cellular and Extracellular Components of Biofilms
10:18

Concurrent Quantification of Cellular and Extracellular Components of Biofilms

Published on: December 10, 2013

8.7K

Related Experiment Videos

Last Updated: Jan 24, 2026

In Vitro Assay to Measure Phosphatidylethanolamine Methyltransferase Activity
09:33

In Vitro Assay to Measure Phosphatidylethanolamine Methyltransferase Activity

Published on: January 5, 2016

10.2K
Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications
14:43

Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications

Published on: September 23, 2013

11.2K
Concurrent Quantification of Cellular and Extracellular Components of Biofilms
10:18

Concurrent Quantification of Cellular and Extracellular Components of Biofilms

Published on: December 10, 2013

8.7K

Area of Science:

  • Biochemistry
  • Cell Biology
  • Molecular Medicine

Background:

  • Phosphatidylethanolamine (PE) is a crucial phospholipid in cell membranes, influencing fluidity, curvature, and vital cellular processes like signaling and membrane trafficking.
  • Despite its abundance, the specific roles of PE in human health and disease are a recent focus of research.
  • Dysregulation of PE levels or metabolism is implicated in metabolic disorders (e.g., NAFLD), neurodegenerative diseases (e.g., Alzheimer's, Parkinson's), and cancers.

Purpose of the Study:

  • To review the physiological functions of phosphatidylethanolamine (PE).
  • To elucidate the mechanisms behind PE-related lipid dysregulation in various human diseases.
  • To highlight the potential of PE lipidomics in identifying disease biomarkers.

Main Methods:

  • Literature review synthesizing current knowledge on PE.
  • Analysis of PE synthesis pathways (CDP-ethanolamine and PSD pathways).
  • Discussion of advancements in lipidomics for PE profiling.

Main Results:

  • PE's conical structure is essential for membrane dynamics and cellular functions.
  • Altered PE metabolism is a common feature in several major human diseases.
  • Lipidomic profiling of PE species offers a promising avenue for biomarker discovery.

Conclusions:

  • Phosphatidylethanolamine plays critical, yet underappreciated, roles in human health.
  • Understanding PE metabolism and its dysregulation is vital for developing novel diagnostic and therapeutic strategies.
  • Advanced lipidomics techniques are instrumental in advancing PE research for disease insights.