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Updated: Jan 24, 2026

Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis
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Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis

Published on: June 27, 2020

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Genomic and Transcriptomic Landscapes of MEN1-Wild-Type Low-Grade Metastatic Pancreatic NETs Uncover Key Oncogenic

Md Hafiz Uddin, Zaid Mahdi, Irfana Muqbil

    Biorxiv : the Preprint Server for Biology
    |January 23, 2026
    PubMed
    Summary

    Metastasis in sporadic pancreatic neuroendocrine tumors (pNETs) with wild-type MEN1 is driven by pathway activation, not just mutation count. This study identifies key molecular signatures and potential targeted therapies for these tumors.

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