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Related Concept Videos

Retrieval01:12

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Retrieval is the process of getting information out of memory storage and back into conscious awareness. This ability is essential for daily tasks like brushing hair and teeth, driving to work, and performing job duties. Retrieval occurs in three ways: recall, recognition, and relearning.
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In the secretory pathway, vesicles transport proteins from one cellular compartment to another in forward transport to deliver the protein to its correct location. Occasionally, misfolded proteins and incorrect proteins escape their original compartments, and a retrieval pathway is used to return the escaped proteins to their original compartment.
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Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
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Fibrous joints are a type of joint where the bones are connected by fibrous connective tissue. These joints provide stability and minimal to no movement between the articulating bones. There are three types of fibrous joints.
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Failure of Universal 2 Wrist Joint Replacements: A Retrieval Study.

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The Universal 2 total wrist arthroplasty showed disappointing long-term results due to polyethylene damage. This was caused by sterilization issues and a design flaw in smaller implants, leading to component failure.

Keywords:
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Area of Science:

  • Orthopedic surgery
  • Biomaterials science
  • Failure analysis

Background:

  • The Universal 2 total wrist arthroplasty, a common implant, exhibited poor long-term outcomes.
  • Failures were linked to significant polyethylene damage and metallosis.

Purpose of the Study:

  • To investigate the root causes of polyethylene damage in retrieved Universal 2 total wrist arthroplasty components.

Main Methods:

  • Retrieval analysis of six Universal 2 wrists and two additional polyethylene components from a single center.
  • Macroscale analysis and dimensional measurements of polyethylene components.
  • Comparison with in vivo component orientation to pinpoint areas of material loss.

Main Results:

  • Smaller implants were revised more frequently, with material loss predominantly on the ulnar side.
  • Polyethylene failure occurred at the base of the ulnar-side blind hole, particularly in smaller sizes with thinner bases.
  • Oxidation, indicated by discoloration and surface fatigue, was observed, with an average in vivo time of 13.8 years.

Conclusions:

  • Polyethylene failure resulted from a combination of improper sterilization and a design flaw making smaller components thinner.
  • Continued surveillance of patients with Universal 2 wrist implants is advised.