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Updated: Jan 24, 2026

05:52
Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
Published on: August 19, 2021
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Management of Suspected Stage IVA Endometrial Cancer With Rectosigmoid Involvement Using Neoadjuvant Chemotherapy and
Yogeeta Gunasagran1, Kenneth Lim2
1Gynaecologic Oncology, Universiti Malaya Medical Centre, Kuala Lumpur, MYS.
Cureus
|January 23, 2026
Summary
Neoadjuvant chemotherapy (NACT) effectively treated advanced endometrial cancer with suspected rectal involvement, enabling less invasive surgery. This approach reduced the need for extensive resection and improved patient outcomes in a rare case.
Area of Science:
- Gynecologic Oncology
- Medical Oncology
- Surgical Oncology
Background:
- Stage IVA endometrial cancer involving the rectosigmoid is rare and poses significant surgical challenges.
- Primary management often risks extensive multivisceral resection and associated morbidity.
- A multidisciplinary team (MDT) approach is crucial for complex cases.
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