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Updated: Jan 24, 2026

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
Published on: December 13, 2017
Successful treatment of refractory generalized granuloma annulare with abrocitinib
Caterina Mariarosaria Giorgio1, Anna Balato1, Gaetano Licata2
1Dermatology Unit, University of Campania "Luigi Vanvitelli", Naples.
Abstract:
Dear Editor, Granuloma annulare is a chronic inflammatory skin disorder characterized by annular dermal papules and plaques. While localized forms often resolve spontaneously, generalized granuloma annulare tends to persist and frequently proves resistant to conventional therapies. The pathogenesis of the disease remains unclear, but increasing evidence suggests a dysregulated immune response involving T cells, macrophages, and cytokines such as tumor necrosis factor-alpha (TNF-α), interleukin (IL)-6, and interferon-gamma (IFN-γ). [...].
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