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Immunotherapy Response Predictive Score Based on Tumor Microenvironment Profiles for Predicting Immunotherapy

Hui-Ching Wang1,2,3,4, Mei-Ren Pan1,2,3,4,5, Leong-Perng Chan3,6

  • 1Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

Technology in Cancer Research & Treatment
|January 23, 2026
PubMed
Summary

A new immune response predictive score (IORPS) accurately identifies patients with recurrent or metastatic head and neck squamous cell carcinoma likely to benefit from immunotherapy, outperforming current biomarkers.

Keywords:
head and neck squamous cell carcinomaimmunotherapyprincipal component analysistranscriptome profilingtumor microenvironment (TME)

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